Advances in chitosan-based hydrogels for pharmaceutical and biomedical applications : A comprehensive review

Copyright © 2023 Elsevier B.V. All rights reserved..

The treatment of diseases, such as cancer, is one of the most significant issues correlated with human beings health. Hydrogels (HGs) prepared from biocompatible and biodegradable materials, especially biopolymers, have been effectively employed for the sort of pharmaceutical and biomedical applications, including drug delivery systems, biosensors, and tissue engineering. Chitosan (CS), one of the most abundant bio-polysaccharide derived from chitin, is an efficient biomaterial in the prognosis, diagnosis, and treatment of diseases. CS-based HGs possess some potential advantages, like high values of bioactive encapsulation, efficient drug delivery to a target site, sustained drug release, good biocompatibility and biodegradability, high serum stability, non-immunogenicity, etc., which made them practical and useful for pharmaceutical and biomedical applications. In this review, we summarize recent achievements and advances associated with CS-based HGs for drug delivery, regenerative medicine, disease detection and therapy.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:253

Enthalten in:

International journal of biological macromolecules - 253(2023), Pt 6 vom: 31. Dez., Seite 127278

Sprache:

Englisch

Beteiligte Personen:

Almajidi, Yasir Qasim [VerfasserIn]
Gupta, Jitendra [VerfasserIn]
Sheri, Fatime Satar [VerfasserIn]
Zabibah, Rahman S [VerfasserIn]
Faisal, Ahmed [VerfasserIn]
Ruzibayev, Akbarali [VerfasserIn]
Adil, Mohaned [VerfasserIn]
Saadh, Mohamed J [VerfasserIn]
Jawad, Mahmood Jasem [VerfasserIn]
Alsaikhan, Fahad [VerfasserIn]
Narmani, Asghar [VerfasserIn]
Farhood, Bagher [VerfasserIn]

Links:

Volltext

Themen:

9012-76-4
Biocompatible Materials
Biosensors
Chitosan
Chitosan hydrogels
Disease therapy
Hydrogels
Journal Article
Pharmaceutical application
Preparation and modification
Regenerative medicine
Review

Anmerkungen:

Date Completed 23.11.2023

Date Revised 23.11.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.ijbiomac.2023.127278

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM363000011