Ultrasensitive quantification of estrogens in serum and plasma by liquid chromatography-tandem mass spectrometry
Copyright © 2023. Published by Elsevier Inc..
Stable isotope dilution (SID) methodology coupled with liquid chromatography-tandem mass spectrometry (LC-MS) is rapidly becoming the gold standard for measuring estrogens in serum and plasma due to improved specificity, high accuracy, and the ability to conduct a more comprehensive analysis. A general consideration of the problems associated with measuring estrogens and two detailed derivatization methods are described in this chapter. These methods quantify estrogens and their metabolites in serum and plasma samples using this state-of-art technology, which is applicable to the routine clinical laboratory.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:689 |
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| Enthalten in: |
Methods in enzymology - 689(2023) vom: 06., Seite 433-452 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wang, Qingqing [VerfasserIn] |
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| Links: |
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| Themen: |
Estradiol |
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| Anmerkungen: |
Date Completed 01.11.2023 Date Revised 22.01.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/bs.mie.2023.04.011 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Stable isotope dilution (SID) methodology coupled with liquid chromatography-tandem mass spectrometry (LC-MS) is rapidly becoming the gold standard for measuring estrogens in serum and plasma due to improved specificity, high accuracy, and the ability to conduct a more comprehensive analysis. A general consideration of the problems associated with measuring estrogens and two detailed derivatization methods are described in this chapter. These methods quantify estrogens and their metabolites in serum and plasma samples using this state-of-art technology, which is applicable to the routine clinical laboratory | ||
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| 650 | 7 | |a Immunologic Factors |2 NLM | |
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| 700 | 1 | |a Mesaros, Clementina |e verfasserin |4 aut | |
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