A Case of Immune Thrombocytopenia Occurring after Radiotherapy plus Atezolizumab Treatment for Bladder Cancer
An 84-year-old female developed gross hematuria. She was diagnosed as urinary bladder carcinoma. She was initiated on concurrent atezolizumab plus radiation(a phase Ⅱ clinical trial)(jRCT2031180060). After 8 cycles of atezolizumab, complete response was confirmed. Maintenance atezolizumab treatment was started. Platelet(Plt)count decreased, there was no rechallenge with atezolizumab. Bone marrow examination revealed normal. Plt count recovered. Plt count decreased again. The serum levels of interleukin-6(IL-6)were elevated. She was diagnosed as having immune thrombocytopenia. She was started on treatment with prednisolone(PSL)at dose of 20 mg/day. Plt count was increased.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:50 |
|---|---|
| Enthalten in: |
Gan to kagaku ryoho. Cancer & chemotherapy - 50(2023), 9 vom: 28. Sept., Seite 985-992 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sekiguchi, Yasunobu [VerfasserIn] |
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| Themen: |
52CMI0WC3Y |
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| Anmerkungen: |
Date Completed 23.10.2023 Date Revised 23.10.2023 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM362939306 |
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| 100 | 1 | |a Sekiguchi, Yasunobu |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A Case of Immune Thrombocytopenia Occurring after Radiotherapy plus Atezolizumab Treatment for Bladder Cancer |
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| 500 | |a Date Completed 23.10.2023 | ||
| 500 | |a Date Revised 23.10.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a An 84-year-old female developed gross hematuria. She was diagnosed as urinary bladder carcinoma. She was initiated on concurrent atezolizumab plus radiation(a phase Ⅱ clinical trial)(jRCT2031180060). After 8 cycles of atezolizumab, complete response was confirmed. Maintenance atezolizumab treatment was started. Platelet(Plt)count decreased, there was no rechallenge with atezolizumab. Bone marrow examination revealed normal. Plt count recovered. Plt count decreased again. The serum levels of interleukin-6(IL-6)were elevated. She was diagnosed as having immune thrombocytopenia. She was started on treatment with prednisolone(PSL)at dose of 20 mg/day. Plt count was increased | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
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| 650 | 7 | |a 52CMI0WC3Y |2 NLM | |
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| 700 | 1 | |a Kanda, Hiroaki |e verfasserin |4 aut | |
| 700 | 1 | |a Kawamura, Machiko |e verfasserin |4 aut | |
| 700 | 1 | |a Kobayashi, Kazuhiko |e verfasserin |4 aut | |
| 700 | 1 | |a Mitani, Koki |e verfasserin |4 aut | |
| 700 | 1 | |a Kurashina, Ryo |e verfasserin |4 aut | |
| 700 | 1 | |a Ikeda, Riko |e verfasserin |4 aut | |
| 700 | 1 | |a Inoue, Masaharu |e verfasserin |4 aut | |
| 700 | 1 | |a Matsuoka, Yoh |e verfasserin |4 aut | |
| 700 | 1 | |a Kageyama, Yukio |e verfasserin |4 aut | |
| 700 | 1 | |a Akaba, Yuki |e verfasserin |4 aut | |
| 700 | 1 | |a Kobayashi, Hirofumi |e verfasserin |4 aut | |
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