Cost-effective device for locating and circumscribing superficial tumors with contrast enhancement and fluorescence quantification

Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved..

BACKGROUND: Two Bispectral contrast enhancement approaches for the fluorescence diagnosis with chlorine-e6 and a wide field-of-view imaging system with fluorescence excitation at 405 nm and time-resolved background suppression were analyzed and compared.

METHODS: Two techniques for the contrast enhancement of a fluorescent video system (Red/Green (R/G) ratio and Red-Green (R-G)) with time-resolved background suppression for fluorescent diagnosis (FD) were tested in four patients with basal cell carcinoma (BCC).

RESULTS: The results of both contrast enhancement methods were compared for the diagnostic efficiency for FD of BCC. Both techniques successfully determined the boundaries of the lesions and the fluorescence intensity.

CONCLUSIONS: Both contrast enhancement modes have proven effective in identifying tumor borders in cases of low contrast in BCC FD with Ce6. While the Red/Green (R/G) mode provides sharper lesion borders, the Red minus Green (R-G) mode visualizes more fluorescent features and makes it easier to assess the lesion margins.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:45

Enthalten in:

Photodiagnosis and photodynamic therapy - 45(2024) vom: 01. Feb., Seite 103827

Sprache:

Englisch

Beteiligte Personen:

Udeneev, A M [VerfasserIn]
Kalyagina, N A [VerfasserIn]
Efendiev, K T [VerfasserIn]
Febenchukova, A A [VerfasserIn]
Kulichenko, A M [VerfasserIn]
Shiryaev, A A [VerfasserIn]
Pisareva, T N [VerfasserIn]
Linkov, K G [VerfasserIn]
Loshchenov, M V [VerfasserIn]

Links:

Volltext

Themen:

405 nm excitation
Background suppression
Basal Cell Carcinoma
Chlorine-e6
Coloring Agents
Contrast enhancement
Fluorescence diagnosis
Journal Article
Multispectral fluorescence imaging
Photosensitizing Agents

Anmerkungen:

Date Completed 04.03.2024

Date Revised 04.03.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.pdpdt.2023.103827

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM362915555