The use of neuropeptides of animal origin in the treatment of neurological diseases
The issues of effective treatment of neurological diseases remain relevant to this day. Neuropeptide preparations have been used in domestic neurological practice for more than 20 years. The physiological activity of neuropeptides is many times greater than that of non-peptide compounds. Neuropeptides include preparations from the brain of animals and synthetically synthesized analogues. The drugs differ from each other not only in composition, but also in different mechanisms of action, while maintaining the commonality of a pronounced neurotrophic and neuroreparative action. Large peptides and amino acids work on the principle of «replacement therapy», minipeptides affect the signaling system of the nuclear erythroid factor and bind to molecular targets, being bioregulators. The specific action of bioregulators is the ability to prolong their action and change the prevailing mechanism by reducing or increasing the required dose when physiologically necessary. They are called SMART-peptides, have high selectivity and efficiency, safety can potentiate the actions of other drugs.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:123 |
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| Enthalten in: |
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 123(2023), 9 vom: 05., Seite 37-42 |
| Sprache: |
Russisch |
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| Weiterer Titel: |
Primenenie neiropeptidov zhivotnogo proiskhozhdeniya v terapii nevrologicheskikh zabolevanii |
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| Beteiligte Personen: |
Putilina, M V [VerfasserIn] |
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| Links: |
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| Themen: |
Amino acids |
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| Anmerkungen: |
Date Completed 01.11.2023 Date Revised 01.11.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.17116/jnevro202312309137 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM362897859 |
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| 245 | 1 | 4 | |a The use of neuropeptides of animal origin in the treatment of neurological diseases |
| 246 | 3 | 3 | |a Primenenie neiropeptidov zhivotnogo proiskhozhdeniya v terapii nevrologicheskikh zabolevanii |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The issues of effective treatment of neurological diseases remain relevant to this day. Neuropeptide preparations have been used in domestic neurological practice for more than 20 years. The physiological activity of neuropeptides is many times greater than that of non-peptide compounds. Neuropeptides include preparations from the brain of animals and synthetically synthesized analogues. The drugs differ from each other not only in composition, but also in different mechanisms of action, while maintaining the commonality of a pronounced neurotrophic and neuroreparative action. Large peptides and amino acids work on the principle of «replacement therapy», minipeptides affect the signaling system of the nuclear erythroid factor and bind to molecular targets, being bioregulators. The specific action of bioregulators is the ability to prolong their action and change the prevailing mechanism by reducing or increasing the required dose when physiologically necessary. They are called SMART-peptides, have high selectivity and efficiency, safety can potentiate the actions of other drugs | ||
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| 650 | 4 | |a SMART-peptides | |
| 650 | 4 | |a amino acids | |
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| 650 | 4 | |a mini-peptides | |
| 650 | 4 | |a neuropeptides of animal origin | |
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| 650 | 7 | |a Peptides |2 NLM | |
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