The Results of the URRAH (Uric Acid Right for Heart Health) Project : A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation
© 2023. The Author(s)..
The relationship between Serum Uric Acid (UA) and Cardiovascular (CV) diseases has already been extensively evaluated, and it was found to be an independent predictor of all-cause and cardiovascular mortality but also acute coronary syndrome, stroke and heart failure. Similarly, also many papers have been published on the association between UA and kidney function, while less is known on the role of UA in metabolic derangement and, particularly, in metabolic syndrome. Despite the substantial number of publications on the topic, there are still some elements of doubt: (1) the better cut-off to be used to refine CV risk (also called CV cut-off); (2) the needing for a correction of UA values for kidney function; and (3) the better definition of its role in metabolic syndrome: is UA simply a marker, a bystander or a key pathological element of metabolic dysregulation?. The Uric acid Right for heArt Health (URRAH) project was designed by the Working Group on uric acid and CV risk of the Italian Society of Hypertension to answer the first question. After the first papers that individuates specific cut-off for different CV disease, subsequent articles have been published responding to the other relevant questions. This review will summarise most of the results obtained so far from the URRAH research project.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
|---|---|
| Enthalten in: |
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension - 30(2023), 5 vom: 04. Sept., Seite 411-425 |
| Sprache: |
Englisch |
|---|
| Links: |
|---|
| Themen: |
268B43MJ25 |
|---|
| Anmerkungen: |
Date Completed 26.10.2023 Date Revised 12.11.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s40292-023-00602-4 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM362860033 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM362860033 | ||
| 003 | DE-627 | ||
| 005 | 20231226092124.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s40292-023-00602-4 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1209.xml |
| 035 | |a (DE-627)NLM362860033 | ||
| 035 | |a (NLM)37792253 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Maloberti, Alessandro |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The Results of the URRAH (Uric Acid Right for Heart Health) Project |b A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 26.10.2023 | ||
| 500 | |a Date Revised 12.11.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023. The Author(s). | ||
| 520 | |a The relationship between Serum Uric Acid (UA) and Cardiovascular (CV) diseases has already been extensively evaluated, and it was found to be an independent predictor of all-cause and cardiovascular mortality but also acute coronary syndrome, stroke and heart failure. Similarly, also many papers have been published on the association between UA and kidney function, while less is known on the role of UA in metabolic derangement and, particularly, in metabolic syndrome. Despite the substantial number of publications on the topic, there are still some elements of doubt: (1) the better cut-off to be used to refine CV risk (also called CV cut-off); (2) the needing for a correction of UA values for kidney function; and (3) the better definition of its role in metabolic syndrome: is UA simply a marker, a bystander or a key pathological element of metabolic dysregulation?. The Uric acid Right for heArt Health (URRAH) project was designed by the Working Group on uric acid and CV risk of the Italian Society of Hypertension to answer the first question. After the first papers that individuates specific cut-off for different CV disease, subsequent articles have been published responding to the other relevant questions. This review will summarise most of the results obtained so far from the URRAH research project | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Cardiovascular diseases | |
| 650 | 4 | |a Kidney function | |
| 650 | 4 | |a Metabolic derangement | |
| 650 | 4 | |a Metabolic syndrome | |
| 650 | 4 | |a URRAH | |
| 650 | 4 | |a Uric acid | |
| 650 | 7 | |a Uric Acid |2 NLM | |
| 650 | 7 | |a 268B43MJ25 |2 NLM | |
| 700 | 1 | |a Mengozzi, Alessandro |e verfasserin |4 aut | |
| 700 | 1 | |a Russo, Elisa |e verfasserin |4 aut | |
| 700 | 1 | |a Cicero, Arrigo Francesco Giuseppe |e verfasserin |4 aut | |
| 700 | 1 | |a Angeli, Fabio |e verfasserin |4 aut | |
| 700 | 1 | |a Agabiti Rosei, Enrico |e verfasserin |4 aut | |
| 700 | 1 | |a Barbagallo, Carlo Maria |e verfasserin |4 aut | |
| 700 | 1 | |a Bernardino, Bruno |e verfasserin |4 aut | |
| 700 | 1 | |a Bombelli, Michele |e verfasserin |4 aut | |
| 700 | 1 | |a Cappelli, Federica |e verfasserin |4 aut | |
| 700 | 1 | |a Casiglia, Edoardo |e verfasserin |4 aut | |
| 700 | 1 | |a Cianci, Rosario |e verfasserin |4 aut | |
| 700 | 1 | |a Ciccarelli, Michele |e verfasserin |4 aut | |
| 700 | 1 | |a Cirillo, Massimo |e verfasserin |4 aut | |
| 700 | 1 | |a Cirillo, Pietro |e verfasserin |4 aut | |
| 700 | 1 | |a Desideri, Giovambattista |e verfasserin |4 aut | |
| 700 | 1 | |a D'Elia, Lanfranco |e verfasserin |4 aut | |
| 700 | 1 | |a Dell'Oro, Raffaella |e verfasserin |4 aut | |
| 700 | 1 | |a Facchetti, Rita |e verfasserin |4 aut | |
| 700 | 1 | |a Ferri, Claudio |e verfasserin |4 aut | |
| 700 | 1 | |a Galletti, Ferruccio |e verfasserin |4 aut | |
| 700 | 1 | |a Giannattasio, Cristina |e verfasserin |4 aut | |
| 700 | 1 | |a Gesualdo, Loreto |e verfasserin |4 aut | |
| 700 | 1 | |a Iaccarino, Guido |e verfasserin |4 aut | |
| 700 | 1 | |a Lippa, Luciano |e verfasserin |4 aut | |
| 700 | 1 | |a Mallamaci, Francesca |e verfasserin |4 aut | |
| 700 | 1 | |a Masi, Stefano |e verfasserin |4 aut | |
| 700 | 1 | |a Masulli, Maria |e verfasserin |4 aut | |
| 700 | 1 | |a Mazza, Alberto |e verfasserin |4 aut | |
| 700 | 1 | |a Muiesan, Maria Lorenza |e verfasserin |4 aut | |
| 700 | 1 | |a Nazzaro, Pietro |e verfasserin |4 aut | |
| 700 | 1 | |a Parati, Gianfranco |e verfasserin |4 aut | |
| 700 | 1 | |a Palatini, Paolo |e verfasserin |4 aut | |
| 700 | 1 | |a Pauletto, Paolo |e verfasserin |4 aut | |
| 700 | 1 | |a Pontremoli, Roberto |e verfasserin |4 aut | |
| 700 | 1 | |a Pugliese, Nicola Riccardo |e verfasserin |4 aut | |
| 700 | 1 | |a Quarti-Trevano, Fosca |e verfasserin |4 aut | |
| 700 | 1 | |a Rattazzi, Marcello |e verfasserin |4 aut | |
| 700 | 1 | |a Reboldi, Gianpaolo |e verfasserin |4 aut | |
| 700 | 1 | |a Rivasi, Giulia |e verfasserin |4 aut | |
| 700 | 1 | |a Salvetti, Massimo |e verfasserin |4 aut | |
| 700 | 1 | |a Tikhonoff, Valerie |e verfasserin |4 aut | |
| 700 | 1 | |a Tocci, Giuliano |e verfasserin |4 aut | |
| 700 | 1 | |a Ungar, Andrea |e verfasserin |4 aut | |
| 700 | 1 | |a Verdecchia, Paolo |e verfasserin |4 aut | |
| 700 | 1 | |a Viazzi, Francesca |e verfasserin |4 aut | |
| 700 | 1 | |a Volpe, Massimo |e verfasserin |4 aut | |
| 700 | 1 | |a Virdis, Agostino |e verfasserin |4 aut | |
| 700 | 1 | |a Grassi, Guido |e verfasserin |4 aut | |
| 700 | 1 | |a Borghi, Claudio |e verfasserin |4 aut | |
| 700 | 0 | |a Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension (SIIA) |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension |d 1997 |g 30(2023), 5 vom: 04. Sept., Seite 411-425 |w (DE-627)NLM09364731X |x 1179-1985 |7 nnns |
| 773 | 1 | 8 | |g volume:30 |g year:2023 |g number:5 |g day:04 |g month:09 |g pages:411-425 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s40292-023-00602-4 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 30 |j 2023 |e 5 |b 04 |c 09 |h 411-425 | ||