Nomogram for predicting postoperative deep vein thrombosis in patients with spinal fractures caused by high-energy injuries

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..

OBJECTIVE: Deep venous thrombosis (DVT) is a common complication in patients with spinal fractures caused by high-energy injuries. Early identification of patients at high risk of postoperative DVT is essential for the prevention of thrombosis. This study aimed to develop and validate a prediction model based on a nomogram to predict DVT in patients with spinal fractures caused by high-energy injuries.

METHODS: Clinical data were collected from 936 patients admitted to our hospital between January 2016 and December 2021 with spinal fractures caused by high-energy injuries. Multivariate logistic regression analysis was used to identify the risk factors for postoperative DVT and to develop a nomogram. The predictive performance of the nomogram was evaluated by the receiver operating characteristic (ROC) curve and calibration curve.

RESULTS: The incidence of preoperative DVT was 15.38% (144/936). The postoperative incidence of DVT was 20.5% (192/936). The multivariate analysis revealed that age, operation time, blood transfusion, duration of bed rest, American Spinal Injury Association (ASIA) score and D-dimer were risk factors for postoperative DVT. The area under the ROC curve of the nomogram was 0.835 and the calibration curve showed good calibration.

CONCLUSIONS: The nomogram showed a good ability to predict postoperative DVT in patients with spinal fractures caused by high-energy injuries, which may benefit pre- and postoperative DVT prophylaxis strategy development.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:144

Enthalten in:

Archives of orthopaedic and trauma surgery - 144(2024), 1 vom: 21. Jan., Seite 171-177

Sprache:

Englisch

Beteiligte Personen:

Lv, Bing [VerfasserIn]
Wang, Haiying [VerfasserIn]
Zhang, Zipeng [VerfasserIn]
Li, Weifeng [VerfasserIn]
Han, Gefeng [VerfasserIn]
Liu, Xiangdong [VerfasserIn]
Zhang, Cheng [VerfasserIn]

Links:

Volltext

Themen:

Deep vein thrombosis
High-energy injury
Journal Article
Nomogram
Prediction model
Spinal fracture

Anmerkungen:

Date Completed 09.01.2024

Date Revised 09.01.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s00402-023-05085-5

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM362858128