Ascaridia galli infection in chicken : Pathobiology and immunological orchestra
© 2023 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd..
BACKGROUND: Ascaridia galli is the largest gut-dwelling helminth of chickens, which confers adverse effects on meat and egg production; thus, on the animal protein supply and the economy. Both adult and immature parasites affect gut health, but larval stages play a major role in pathology.
AIMS: Here, we present immunology and pathology of A. galli in chickens.
MATERIALS AND METHODS: Literatures were surveyed through online platforms such as PubMed, Google Scholar and Researchgate.
RESULTS: The larvae cause excessive mucus production, damage to the intestinal gland, hemorrhage, anemia, diarrhea, and malnutrition. The adult worms can cause death by intestinal obstruction and intussusception. Although both cellular and humoral immunity are involved in fighting against ascariasis, the role of naturally acquired immunity is poorly defined. In cellular immunity, Th-2 cytokines (IL-4, IL-5, IL-9, and IL-13), goblet cells (mucin), gut-associated lymphoid tissues, CD8α+ intraepithelial cells, TCRγδ + T cells, and TGF-β4 form a protective band. Type 2 immunity provides protection by forming a network of endogenous damage-associated molecular patterns, chitin, and parasitic antigens. Among antibodies, IgY is the most prominent in chickens and provides temporary humoral protection. During parasitic infection, infiltration of various immune cells is evident, especially in the intestinal epithelium, lamina propria, and crypts of the duodenum and jejunum. In chickens older than 12 weeks, gradual reduction of worm burden is more successful than the younger birds. Female chickens exert a short-lived but higher level of protection by passing IgY to chicks in the form of egg yolk antibodies. In laying conditions, immunity differs between breeds. This review provides an overview of the silent but inevitable pathological changes induced by A. galli and the interaction of host immunity with the parasite.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
|---|---|
| Enthalten in: |
Immunity, inflammation and disease - 11(2023), 9 vom: 29. Sept., Seite e1001 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Shohana, Nusrat Nowrin [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Age, sex and breed specific immunity |
|---|
| Anmerkungen: |
Date Completed 04.10.2023 Date Revised 13.10.2023 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1002/iid3.1001 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM362698848 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM362698848 | ||
| 003 | DE-627 | ||
| 005 | 20231226091757.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/iid3.1001 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1208.xml |
| 035 | |a (DE-627)NLM362698848 | ||
| 035 | |a (NLM)37773698 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Shohana, Nusrat Nowrin |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Ascaridia galli infection in chicken |b Pathobiology and immunological orchestra |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 04.10.2023 | ||
| 500 | |a Date Revised 13.10.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd. | ||
| 520 | |a BACKGROUND: Ascaridia galli is the largest gut-dwelling helminth of chickens, which confers adverse effects on meat and egg production; thus, on the animal protein supply and the economy. Both adult and immature parasites affect gut health, but larval stages play a major role in pathology | ||
| 520 | |a AIMS: Here, we present immunology and pathology of A. galli in chickens | ||
| 520 | |a MATERIALS AND METHODS: Literatures were surveyed through online platforms such as PubMed, Google Scholar and Researchgate | ||
| 520 | |a RESULTS: The larvae cause excessive mucus production, damage to the intestinal gland, hemorrhage, anemia, diarrhea, and malnutrition. The adult worms can cause death by intestinal obstruction and intussusception. Although both cellular and humoral immunity are involved in fighting against ascariasis, the role of naturally acquired immunity is poorly defined. In cellular immunity, Th-2 cytokines (IL-4, IL-5, IL-9, and IL-13), goblet cells (mucin), gut-associated lymphoid tissues, CD8α+ intraepithelial cells, TCRγδ + T cells, and TGF-β4 form a protective band. Type 2 immunity provides protection by forming a network of endogenous damage-associated molecular patterns, chitin, and parasitic antigens. Among antibodies, IgY is the most prominent in chickens and provides temporary humoral protection. During parasitic infection, infiltration of various immune cells is evident, especially in the intestinal epithelium, lamina propria, and crypts of the duodenum and jejunum. In chickens older than 12 weeks, gradual reduction of worm burden is more successful than the younger birds. Female chickens exert a short-lived but higher level of protection by passing IgY to chicks in the form of egg yolk antibodies. In laying conditions, immunity differs between breeds. This review provides an overview of the silent but inevitable pathological changes induced by A. galli and the interaction of host immunity with the parasite | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Ascaridia galli | |
| 650 | 4 | |a Immunology | |
| 650 | 4 | |a age, sex and breed specific immunity | |
| 650 | 4 | |a maternal immunity | |
| 650 | 4 | |a pathology | |
| 650 | 7 | |a Cytokines |2 NLM | |
| 650 | 7 | |a Antibodies |2 NLM | |
| 700 | 1 | |a Rony, Sharmin Aqter |e verfasserin |4 aut | |
| 700 | 1 | |a Ali, Md Haydar |e verfasserin |4 aut | |
| 700 | 1 | |a Hossain, Md Shahadat |e verfasserin |4 aut | |
| 700 | 1 | |a Labony, Sharmin Shahid |e verfasserin |4 aut | |
| 700 | 1 | |a Dey, Anita Rani |e verfasserin |4 aut | |
| 700 | 1 | |a Farjana, Thahsin |e verfasserin |4 aut | |
| 700 | 1 | |a Alam, Mohammad Zahangir |e verfasserin |4 aut | |
| 700 | 1 | |a Alim, Md Abdul |e verfasserin |4 aut | |
| 700 | 1 | |a Anisuzzaman |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Immunity, inflammation and disease |d 2013 |g 11(2023), 9 vom: 29. Sept., Seite e1001 |w (DE-627)NLM243574827 |x 2050-4527 |7 nnns |
| 773 | 1 | 8 | |g volume:11 |g year:2023 |g number:9 |g day:29 |g month:09 |g pages:e1001 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1002/iid3.1001 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 11 |j 2023 |e 9 |b 29 |c 09 |h e1001 | ||