Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study
BACKGROUND: It is important to determine the influence of traditional risk factors on the development of type 2 diabetes mellitus (T2DM) in young adults. Goal of the research: To study the incidence of T2DM and factors that increase the risk of its occurrence during the observation of a cohort of young adults.
MATERIALS AND METHODS: 1341 people aged 25-44 were included in the study from 2013 to 2017, of whom 622 were men (46.4%). The examination included anamnesis, anthropometric data, and a blood test. Cases of developed T2DM were identified by comparing the Diabetes Mellitus Register, medical records of patients, and the database of examined individuals from 2019 to 2023. T2DM Results: In the examined population, 11 participants (0.82%) developed T2DM. The prevalence of T2DM was 0.96% in men and 0.69% in women. Patients with T2DM had a higher waist circumference, BMI, SBP, TG, and lower HDL than patients without T2DM, and were also less likely to have a higher education. The risk of developing T2DM increases 6.5 times at a BMI of ≥30 kg/m2, and 5.2 times at a TG level of ≥1.7 mmol/L, regardless of other risk factors. In the absence of a higher education, the risk of developing T2DM is increased by 5.6 times.
CONCLUSION: In young people, high triglyceride levels, obesity, and a low level of education are associated with the risk of developing type 2 diabetes, regardless of other factors.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
Journal of personalized medicine - 13(2023), 9 vom: 19. Sept. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Garbuzova, Evgeniia V [VerfasserIn] |
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| Links: |
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| Themen: |
Cohort study |
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| Anmerkungen: |
Date Revised 03.10.2023 published: Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.3390/jpm13091403 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM362594368 |
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| 100 | 1 | |a Garbuzova, Evgeniia V |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study |
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| 500 | |a published: Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a BACKGROUND: It is important to determine the influence of traditional risk factors on the development of type 2 diabetes mellitus (T2DM) in young adults. Goal of the research: To study the incidence of T2DM and factors that increase the risk of its occurrence during the observation of a cohort of young adults | ||
| 520 | |a MATERIALS AND METHODS: 1341 people aged 25-44 were included in the study from 2013 to 2017, of whom 622 were men (46.4%). The examination included anamnesis, anthropometric data, and a blood test. Cases of developed T2DM were identified by comparing the Diabetes Mellitus Register, medical records of patients, and the database of examined individuals from 2019 to 2023. T2DM Results: In the examined population, 11 participants (0.82%) developed T2DM. The prevalence of T2DM was 0.96% in men and 0.69% in women. Patients with T2DM had a higher waist circumference, BMI, SBP, TG, and lower HDL than patients without T2DM, and were also less likely to have a higher education. The risk of developing T2DM increases 6.5 times at a BMI of ≥30 kg/m2, and 5.2 times at a TG level of ≥1.7 mmol/L, regardless of other risk factors. In the absence of a higher education, the risk of developing T2DM is increased by 5.6 times | ||
| 520 | |a CONCLUSION: In young people, high triglyceride levels, obesity, and a low level of education are associated with the risk of developing type 2 diabetes, regardless of other factors | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a cohort study | |
| 650 | 4 | |a educational status | |
| 650 | 4 | |a hypertriglyceridemia | |
| 650 | 4 | |a obesity | |
| 650 | 4 | |a persons 25–44 years old | |
| 650 | 4 | |a type 2 diabetes mellitus | |
| 700 | 1 | |a Shcherbakova, Lilia V |e verfasserin |4 aut | |
| 700 | 1 | |a Rymar, Oksana D |e verfasserin |4 aut | |
| 700 | 1 | |a Khudiakova, Alyona D |e verfasserin |4 aut | |
| 700 | 1 | |a Shramko, Victoria S |e verfasserin |4 aut | |
| 700 | 1 | |a Ragino, Yulia I |e verfasserin |4 aut | |
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