Epidemiology, Ventilation Management and Outcomes of COPD Patients Receiving Invasive Ventilation for COVID-19-Insights from PRoVENT-COVID
Chronic obstructive pulmonary disease (COPD) is a risk factor for death in patients admitted to intensive care units (ICUs) for respiratory support. Previous reports suggested higher mortality in COPD patients with COVID-19. It is yet unknown whether patients with COPD were treated differently compared to non-COPD patients. We compared the ventilation management and outcomes of invasive ventilation for COVID-19 in COPD patients versus non-COPD patients. This was a post hoc analysis of a nation-wide, observational study in the Netherlands. COPD patients were compared to non-COPD patients with respect to key ventilation parameters. The secondary endpoints included adjunctive treatments for refractory hypoxemia, and 28-day mortality. Of a total of 1090 patients, 88 (8.1%) were classified as having COPD. The ventilation parameters were not different between COPD patients and non-COPD patients, except for FiO2, which was higher in COPD patients. Prone positioning was applied more often in COPD patients. COPD patients had higher 28-day mortality than non-COPD patients. COPD had an independent association with 28-day mortality. In this cohort of patients who received invasive ventilation for COVID-19, only FiO2 settings and the use of prone positioning were different between COPD patients and non-COPD patients. COPD patients had higher mortality than non-COPD patients.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
|---|---|
| Enthalten in: |
Journal of clinical medicine - 12(2023), 18 vom: 05. Sept. |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Tripipitsiriwat, Athiwat [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
ARDS |
|---|
| Anmerkungen: |
Date Revised 09.11.2023 published: Electronic Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.3390/jcm12185783 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM362589925 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM362589925 | ||
| 003 | DE-627 | ||
| 005 | 20231226091544.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3390/jcm12185783 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1208.xml |
| 035 | |a (DE-627)NLM362589925 | ||
| 035 | |a (NLM)37762725 | ||
| 035 | |a (PII)5783 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Tripipitsiriwat, Athiwat |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Epidemiology, Ventilation Management and Outcomes of COPD Patients Receiving Invasive Ventilation for COVID-19-Insights from PRoVENT-COVID |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 09.11.2023 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Chronic obstructive pulmonary disease (COPD) is a risk factor for death in patients admitted to intensive care units (ICUs) for respiratory support. Previous reports suggested higher mortality in COPD patients with COVID-19. It is yet unknown whether patients with COPD were treated differently compared to non-COPD patients. We compared the ventilation management and outcomes of invasive ventilation for COVID-19 in COPD patients versus non-COPD patients. This was a post hoc analysis of a nation-wide, observational study in the Netherlands. COPD patients were compared to non-COPD patients with respect to key ventilation parameters. The secondary endpoints included adjunctive treatments for refractory hypoxemia, and 28-day mortality. Of a total of 1090 patients, 88 (8.1%) were classified as having COPD. The ventilation parameters were not different between COPD patients and non-COPD patients, except for FiO2, which was higher in COPD patients. Prone positioning was applied more often in COPD patients. COPD patients had higher 28-day mortality than non-COPD patients. COPD had an independent association with 28-day mortality. In this cohort of patients who received invasive ventilation for COVID-19, only FiO2 settings and the use of prone positioning were different between COPD patients and non-COPD patients. COPD patients had higher mortality than non-COPD patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a ARDS | |
| 650 | 4 | |a COPD | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a invasive ventilation | |
| 650 | 4 | |a outcome | |
| 650 | 4 | |a ventilation management | |
| 700 | 1 | |a Suppapueng, Orawan |e verfasserin |4 aut | |
| 700 | 1 | |a van Meenen, David M P |e verfasserin |4 aut | |
| 700 | 1 | |a Paulus, Frederique |e verfasserin |4 aut | |
| 700 | 1 | |a Hollmann, Markus W |e verfasserin |4 aut | |
| 700 | 1 | |a Sivakorn, Chaisith |e verfasserin |4 aut | |
| 700 | 1 | |a Schultz, Marcus J |e verfasserin |4 aut | |
| 700 | 0 | |a PRoVENT-COVID Investigators |e verfasserin |4 aut | |
| 700 | 1 | |a Ahuja, S |e investigator |4 oth | |
| 700 | 1 | |a van Akkeren, J P |e investigator |4 oth | |
| 700 | 1 | |a Algera, A G |e investigator |4 oth | |
| 700 | 1 | |a Algoe, K C |e investigator |4 oth | |
| 700 | 1 | |a van Amstel, R B |e investigator |4 oth | |
| 700 | 1 | |a van de Berg, P |e investigator |4 oth | |
| 700 | 1 | |a Bergmans, D C |e investigator |4 oth | |
| 700 | 1 | |a van den Bersselaar, D I |e investigator |4 oth | |
| 700 | 1 | |a Bertens, F A |e investigator |4 oth | |
| 700 | 1 | |a Bindels, A J |e investigator |4 oth | |
| 700 | 1 | |a Breel, J S |e investigator |4 oth | |
| 700 | 1 | |a Bruna, M M |e investigator |4 oth | |
| 700 | 1 | |a de Boer, S |e investigator |4 oth | |
| 700 | 1 | |a Boers, L S |e investigator |4 oth | |
| 700 | 1 | |a Botta, M |e investigator |4 oth | |
| 700 | 1 | |a Baur, O L |e investigator |4 oth | |
| 700 | 1 | |a de Bruin, H |e investigator |4 oth | |
| 700 | 1 | |a Buiteman–Kruizinga, L A |e investigator |4 oth | |
| 700 | 1 | |a Cremer, O |e investigator |4 oth | |
| 700 | 1 | |a Determann, R M |e investigator |4 oth | |
| 700 | 1 | |a Dieperink, W |e investigator |4 oth | |
| 700 | 1 | |a van Dijk, J |e investigator |4 oth | |
| 700 | 1 | |a Dongelmans, D A |e investigator |4 oth | |
| 700 | 1 | |a de Graaff, M J |e investigator |4 oth | |
| 700 | 1 | |a Galekaldridge, M S |e investigator |4 oth | |
| 700 | 1 | |a Hagens, L A |e investigator |4 oth | |
| 700 | 1 | |a Haringman, J J |e investigator |4 oth | |
| 700 | 1 | |a van der Heide, S T |e investigator |4 oth | |
| 700 | 1 | |a van der Heiden, P L |e investigator |4 oth | |
| 700 | 1 | |a Hoeijmakers, L L |e investigator |4 oth | |
| 700 | 1 | |a Hol, L |e investigator |4 oth | |
| 700 | 1 | |a Hollmann, M W |e investigator |4 oth | |
| 700 | 1 | |a Horn, J |e investigator |4 oth | |
| 700 | 1 | |a van der Horst, E |e investigator |4 oth | |
| 700 | 1 | |a Le, E L |e investigator |4 oth | |
| 700 | 1 | |a Ivanov, D |e investigator |4 oth | |
| 700 | 1 | |a Juffermans, N P |e investigator |4 oth | |
| 700 | 1 | |a Kho, E |e investigator |4 oth | |
| 700 | 1 | |a de Klerk, E S |e investigator |4 oth | |
| 700 | 1 | |a Koopman, A W |e investigator |4 oth | |
| 700 | 1 | |a Koopmans, M |e investigator |4 oth | |
| 700 | 1 | |a Kucukcelebi, I |e investigator |4 oth | |
| 700 | 1 | |a Kuiper, M A |e investigator |4 oth | |
| 700 | 1 | |a de Lange, D W |e investigator |4 oth | |
| 700 | 1 | |a Martin-Loeches, I |e investigator |4 oth | |
| 700 | 1 | |a Mazzinari, G |e investigator |4 oth | |
| 700 | 1 | |a van Meenen, D M |e investigator |4 oth | |
| 700 | 1 | |a van Mourik, N |e investigator |4 oth | |
| 700 | 1 | |a Nijbroek, S G |e investigator |4 oth | |
| 700 | 1 | |a Oostdijk, E A |e investigator |4 oth | |
| 700 | 1 | |a Paulus, F |e investigator |4 oth | |
| 700 | 1 | |a Sleeswijk, M E |e investigator |4 oth | |
| 700 | 1 | |a Spronk, P E |e investigator |4 oth | |
| 700 | 1 | |a Strang, A C |e investigator |4 oth | |
| 700 | 1 | |a Stilma, W |e investigator |4 oth | |
| 700 | 1 | |a Swart, P |e investigator |4 oth | |
| 700 | 1 | |a Tsonas, A M |e investigator |4 oth | |
| 700 | 1 | |a Valk, C M A |e investigator |4 oth | |
| 700 | 1 | |a Vlaar, A P |e investigator |4 oth | |
| 700 | 1 | |a Veldhuis, L I |e investigator |4 oth | |
| 700 | 1 | |a van der Ven, W H |e investigator |4 oth | |
| 700 | 1 | |a van Velzen, P |e investigator |4 oth | |
| 700 | 1 | |a van Vilet, P |e investigator |4 oth | |
| 700 | 1 | |a van der Voort, P |e investigator |4 oth | |
| 700 | 1 | |a van Welie, L |e investigator |4 oth | |
| 700 | 1 | |a van Wijk, B |e investigator |4 oth | |
| 700 | 1 | |a Winters, T |e investigator |4 oth | |
| 700 | 1 | |a Wong, W Y |e investigator |4 oth | |
| 700 | 1 | |a van Zanten, A R |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of clinical medicine |d 2012 |g 12(2023), 18 vom: 05. Sept. |w (DE-627)NLM230666310 |x 2077-0383 |7 nnns |
| 773 | 1 | 8 | |g volume:12 |g year:2023 |g number:18 |g day:05 |g month:09 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3390/jcm12185783 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 12 |j 2023 |e 18 |b 05 |c 09 | ||