Thyroid FNA cytology : Impact of the COVID-19 pandemic and vaccination in a Brazilian series
© 2023 American Cancer Society..
BACKGROUND: The coronavirus disease 2019 pandemic prompted changes in medical practice, with a reduction in cytopathology volumes and a relative increase in the malignancy rate during lockdown and the initial postlockdown period. To date, no study has evaluated the impact of these changes on the volume of rapid on-site evaluation (ROSE) or on the frequency of cases according to The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) categories after vaccination.
METHODS: Ultrasound-guided thyroid fine-needle aspiration (FNA) and ROSE assessments performed from January 2019 to May 2022 were evaluated retrospectively according to TBSRTC categories for three periods: prepandemic (period 1), from transmission to expansion (period 2), and after vaccination (period 3).
RESULTS: There were 7531 nodules from 5815 patients. FNA cases increased throughout the pandemic despite a drop during lockdown. The frequency of TBSRTC categories changed. Nondiagnostic cases had an increase of 18.1% in period 2 and 76.2% after vaccination compared with prepandemic levels. Malignant cases increased from 2.3% to 4.2% in period 2 and to 5.1% in period 3, representing increases of 83.1% and 121.2%, respectively, compared with period 1. Data corrected by time showed increases in categories IV, V, and VI and a decrease in benign nodules during the two pandemic periods. ROSE was performed in 787 cases during the prepandemic period, and there were decreases of 29.4% and 22.8% in periods 2 and 3, respectively. The ROSE-to-category I ratio was reduced significantly after vaccination.
CONCLUSIONS: Increased volume with sustained lower benign rates and higher malignant rates before and after vaccination indicate better selection of patients for FNA. A worse adequacy rate was correlated with a decrease in the number of ROSE assessments.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:132 |
|---|---|
| Enthalten in: |
Cancer cytopathology - 132(2024), 1 vom: 02. Jan., Seite 22-29 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
de Andrade Natal, Rodrigo [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Bethesda classification |
|---|
| Anmerkungen: |
Date Completed 03.01.2024 Date Revised 03.01.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1002/cncy.22763 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM362438773 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM362438773 | ||
| 003 | DE-627 | ||
| 005 | 20240108141219.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/cncy.22763 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1247.xml |
| 035 | |a (DE-627)NLM362438773 | ||
| 035 | |a (NLM)37747447 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a de Andrade Natal, Rodrigo |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Thyroid FNA cytology |b Impact of the COVID-19 pandemic and vaccination in a Brazilian series |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 03.01.2024 | ||
| 500 | |a Date Revised 03.01.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 American Cancer Society. | ||
| 520 | |a BACKGROUND: The coronavirus disease 2019 pandemic prompted changes in medical practice, with a reduction in cytopathology volumes and a relative increase in the malignancy rate during lockdown and the initial postlockdown period. To date, no study has evaluated the impact of these changes on the volume of rapid on-site evaluation (ROSE) or on the frequency of cases according to The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) categories after vaccination | ||
| 520 | |a METHODS: Ultrasound-guided thyroid fine-needle aspiration (FNA) and ROSE assessments performed from January 2019 to May 2022 were evaluated retrospectively according to TBSRTC categories for three periods: prepandemic (period 1), from transmission to expansion (period 2), and after vaccination (period 3) | ||
| 520 | |a RESULTS: There were 7531 nodules from 5815 patients. FNA cases increased throughout the pandemic despite a drop during lockdown. The frequency of TBSRTC categories changed. Nondiagnostic cases had an increase of 18.1% in period 2 and 76.2% after vaccination compared with prepandemic levels. Malignant cases increased from 2.3% to 4.2% in period 2 and to 5.1% in period 3, representing increases of 83.1% and 121.2%, respectively, compared with period 1. Data corrected by time showed increases in categories IV, V, and VI and a decrease in benign nodules during the two pandemic periods. ROSE was performed in 787 cases during the prepandemic period, and there were decreases of 29.4% and 22.8% in periods 2 and 3, respectively. The ROSE-to-category I ratio was reduced significantly after vaccination | ||
| 520 | |a CONCLUSIONS: Increased volume with sustained lower benign rates and higher malignant rates before and after vaccination indicate better selection of patients for FNA. A worse adequacy rate was correlated with a decrease in the number of ROSE assessments | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Bethesda classification | |
| 650 | 4 | |a coronavirus disease 2019 (COVID-19) | |
| 650 | 4 | |a cytopathology | |
| 650 | 4 | |a fine-needle aspiration | |
| 650 | 4 | |a thyroid | |
| 700 | 1 | |a Bedin, Afonso Resende |e verfasserin |4 aut | |
| 700 | 1 | |a Giongo, Aline Alencar |e verfasserin |4 aut | |
| 700 | 1 | |a Dias, Everton Mesquita |e verfasserin |4 aut | |
| 700 | 1 | |a Paschoalini, Rafael Bispo |e verfasserin |4 aut | |
| 700 | 1 | |a Volpato, Arthur Henrique Cunha |e verfasserin |4 aut | |
| 700 | 1 | |a Melo, André Luís Alves de |e verfasserin |4 aut | |
| 700 | 1 | |a Santos, Caio de Carvalho |e verfasserin |4 aut | |
| 700 | 1 | |a Delgado, Ana Lídia Jacintho |e verfasserin |4 aut | |
| 700 | 1 | |a Dufloth, Rozany Mucha |e verfasserin |4 aut | |
| 700 | 1 | |a Soares, Fernando Augusto |e verfasserin |4 aut | |
| 700 | 1 | |a da Cunha Santos, Gilda |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cancer cytopathology |d 1999 |g 132(2024), 1 vom: 02. Jan., Seite 22-29 |w (DE-627)NLM104669381 |x 1934-6638 |7 nnns |
| 773 | 1 | 8 | |g volume:132 |g year:2024 |g number:1 |g day:02 |g month:01 |g pages:22-29 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1002/cncy.22763 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 132 |j 2024 |e 1 |b 02 |c 01 |h 22-29 | ||