Improving the physicochemical stability and release properties of curcumin using κ-carrageenan/scallop hydrolysates hydrogel beads

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Scallop (Patinopecten yessoensis) male gonad hydrolysates (SMGHs)/κ-carrageenan (KC)/KCl beads with SMGHs:KC ratios (0:10-5:5) were investigated. SMGHs/KC/KCl-Cur bead (5:5) exhibited the most intact spherical morphology and highest Cur loading content of 0.063 mg/0.1 g bead, ascribing to a shortened T23 from 1607.9 to 966.4 ms, and red and blueshifts of OH, NH, amide I and II bands. The undetected fingerprint region within 7.82°-28.90° of SMGHs/KC/KCl-Cur beads indicated successful Cur entrapment. Moreover, SMGHs/KC/KCl-Cur beads exhibited shrinkage network backbones and larger void pores as SMGHs increased, with vessel percentage area, total number of junctions, total vessel length decreasing from 52.1, 1446.8, 57931.4 to 39.7, 530.5, 34458.4, and lacunarity increasing from 0.048 to 0.111, respectively. Furthermore, Cur showed approximately 50% release contents in colon phase and above 90% retention rate during 30 days of storage at 4 °C. These results suggested that SMGHs/KC/KCl-Cur beads exhibited sustained-release of Cur and promised stable Cur preservation.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

2023

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:434

Enthalten in:

Food chemistry - 434(2023) vom: 15. Feb., Seite 137471

Sprache:

Englisch

Beteiligte Personen:

Yan, Jia-Nan [VerfasserIn]
Wang, Yu-Qiao [VerfasserIn]
Zhang, Zhu-Jun [VerfasserIn]
Du, Yi-Nan [VerfasserIn]
Wu, Hai-Tao [VerfasserIn]

Links:

Volltext

Themen:

κ-Carrageenan
9000-07-1
Beads
Carrageenan
Curcumin
Drug Carriers
Hydrogels
IT942ZTH98
Journal Article
Preservation
Scallop
Sustained-release

Anmerkungen:

Date Completed 12.10.2023

Date Revised 18.10.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.foodchem.2023.137471

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM362377227