Valproate-induced burning mouth syndrome in a male with fibromyalgia and bipolar spectrum disorder

Burning mouth syndrome is a chronic painful condition characterized by a subjective intraoral pain and burning sensations in the absence of an identifiable medical, dental, or psychiatric cause. Although the underlying etiology is currently unclear, an idiopathic (or primary) form and a secondary form to other conditions are formally recognized. However, as several authors have suggested, it might be of clinical utility to consider the existence of a third clinical entity, namely Drug-Induced Burning mouth syndrome, for its therapeutic implications. The latter has been reported with angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, antiretrovirals, anticoagulants, chemotherapy, and drugs commonly used in the treatment of neuropsychiatric disorders such as antidepressants, benzodiazepines, and antipsychotics. Regarding anticonvulsants a literature search found a previous case of Topiramate-Induced Burning mouth syndrome but no previous report of valproate-induced Burning mouth syndrome. Our case is, to date, the first case in the literature of Burning mouth syndrome onset following the administration of valproate to a patient suffering from fibromyalgia and bipolar spectrum disorder. Symptoms resolved completely when the drug was stopped, and the association between symptoms and drug was replicated after drug re-administration.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:10

Enthalten in:

Archive of clinical cases - 10(2023), 3 vom: 01., Seite 125-127

Sprache:

Englisch

Beteiligte Personen:

Raia, Accursio [VerfasserIn]
Caruso, Valerio [VerfasserIn]
Montalbano, Clara [VerfasserIn]
Migli, Lavinia [VerfasserIn]
Raia, Calogero [VerfasserIn]
Pini, Stefano [VerfasserIn]

Links:

Volltext

Themen:

Bipolar disorder
Burning mouth syndrome
Case Reports
Fibromyalgia
Neuropathic pain
Stomatodynia
Valproate

Anmerkungen:

Date Revised 23.09.2023

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.22551/2023.40.1003.10257

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM362331944