Bioelectronic medicine potentiates endogenous NSCs for neurodegenerative diseases
Copyright © 2023 Elsevier Ltd. All rights reserved..
Neurodegenerative diseases (NDs) are commonly observed and while no therapy is universally applicable, cell-based therapies are promising. Stem cell transplantation has been investigated, but endogenous neural stem cells (eNSCs), despite their potential, especially with the development of bioelectronic medicine and biomaterials, remain understudied. Here, we compare stem cell transplantation therapy with eNSC-based therapy and summarize the combined use of eNSCs and developing technologies. The rapid development of implantable biomaterials has resulted in electronic stimulation becoming increasingly effective and decreasingly invasive. Thus, the combination of bioelectronic medicine and eNSCs has substantial potential for the treatment of NDs.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:29 |
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| Enthalten in: |
Trends in molecular medicine - 29(2023), 11 vom: 19. Nov., Seite 886-896 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yu, Maifu [VerfasserIn] |
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| Links: |
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| Themen: |
Electronic stimulation |
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| Anmerkungen: |
Date Revised 13.10.2023 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.molmed.2023.08.005 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Neurodegenerative diseases (NDs) are commonly observed and while no therapy is universally applicable, cell-based therapies are promising. Stem cell transplantation has been investigated, but endogenous neural stem cells (eNSCs), despite their potential, especially with the development of bioelectronic medicine and biomaterials, remain understudied. Here, we compare stem cell transplantation therapy with eNSC-based therapy and summarize the combined use of eNSCs and developing technologies. The rapid development of implantable biomaterials has resulted in electronic stimulation becoming increasingly effective and decreasingly invasive. Thus, the combination of bioelectronic medicine and eNSCs has substantial potential for the treatment of NDs | ||
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