The effectiveness of fascial closure with antimicrobial-coated sutures in preventing incisional surgical site infections in gastrointestinal surgery : a systematic review and meta-analysis
Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved..
The aim of this study was to conduct a systematic review and meta-analysis of the efficacy of fascial closure using antimicrobial-sutures specifically for the prevention of surgical site infections (SSIs) in gastrointestinal surgery, as part of the revision of the SSI prevention guidelines of the Japanese Society of Surgical Infectious Diseases (JSSI). We searched CENTRAL, PubMed and ICHUSHI-Web in May 2023, and included randomized controlled trials (RCTs) comparing antimicrobial-coated and non-coated sutures for fascial closure in gastrointestinal surgery (PROSPERO No. CRD42023430377). Three authors independently screened the RCTs. We assessed the risk of bias and the GRADE criteria for the extracted data. The primary outcome was incisional SSI and the secondary outcomes were abdominal wall dehiscence and the length of postoperative hospital stay. This study was supported partially by the JSSI. A total of 10 RCTs and 5396 patients were included. The use of antimicrobial-coated sutures significantly lowered the risk of incisional SSIs compared with non-coated suture (risk ratio: 0.79, 95% confidence intervals: 0.64-0.98). In subgroup analyses, antimicrobial-coated sutures reduced the risk of SSIs for open surgeries, and when monofilament sutures were used. Antimicrobial-coated sutures did not reduce the incidence of abdominal wall dehiscence and the length of hospital stay compared with non-coated sutures. The certainty of the evidence was rated as moderate according to the GRADE criteria, because of risk of bias. In conclusion, the use of antimicrobial-coated sutures for fascial closure in gastrointestinal surgery is associated with a significantly lower risk of SSI than non-coated sutures.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:146 |
|---|---|
| Enthalten in: |
The Journal of hospital infection - 146(2024) vom: 21. Apr., Seite 174-182 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Kouzu, K [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Anti-Infective Agents |
|---|
| Anmerkungen: |
Date Completed 22.04.2024 Date Revised 22.04.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.jhin.2023.09.006 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM36231277X |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM36231277X | ||
| 003 | DE-627 | ||
| 005 | 20240422231936.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.jhin.2023.09.006 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1383.xml |
| 035 | |a (DE-627)NLM36231277X | ||
| 035 | |a (NLM)37734678 | ||
| 035 | |a (PII)S0195-6701(23)00293-1 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Kouzu, K |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The effectiveness of fascial closure with antimicrobial-coated sutures in preventing incisional surgical site infections in gastrointestinal surgery |b a systematic review and meta-analysis |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 22.04.2024 | ||
| 500 | |a Date Revised 22.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved. | ||
| 520 | |a The aim of this study was to conduct a systematic review and meta-analysis of the efficacy of fascial closure using antimicrobial-sutures specifically for the prevention of surgical site infections (SSIs) in gastrointestinal surgery, as part of the revision of the SSI prevention guidelines of the Japanese Society of Surgical Infectious Diseases (JSSI). We searched CENTRAL, PubMed and ICHUSHI-Web in May 2023, and included randomized controlled trials (RCTs) comparing antimicrobial-coated and non-coated sutures for fascial closure in gastrointestinal surgery (PROSPERO No. CRD42023430377). Three authors independently screened the RCTs. We assessed the risk of bias and the GRADE criteria for the extracted data. The primary outcome was incisional SSI and the secondary outcomes were abdominal wall dehiscence and the length of postoperative hospital stay. This study was supported partially by the JSSI. A total of 10 RCTs and 5396 patients were included. The use of antimicrobial-coated sutures significantly lowered the risk of incisional SSIs compared with non-coated suture (risk ratio: 0.79, 95% confidence intervals: 0.64-0.98). In subgroup analyses, antimicrobial-coated sutures reduced the risk of SSIs for open surgeries, and when monofilament sutures were used. Antimicrobial-coated sutures did not reduce the incidence of abdominal wall dehiscence and the length of hospital stay compared with non-coated sutures. The certainty of the evidence was rated as moderate according to the GRADE criteria, because of risk of bias. In conclusion, the use of antimicrobial-coated sutures for fascial closure in gastrointestinal surgery is associated with a significantly lower risk of SSI than non-coated sutures | ||
| 650 | 4 | |a Meta-Analysis | |
| 650 | 4 | |a Systematic Review | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Antimicrobial-coated sutures | |
| 650 | 4 | |a Fascial closure | |
| 650 | 4 | |a Gastrointestinal surgery | |
| 650 | 4 | |a Surgical site infections | |
| 650 | 7 | |a Anti-Infective Agents |2 NLM | |
| 700 | 1 | |a Tsujimoto, H |e verfasserin |4 aut | |
| 700 | 1 | |a Ishinuki, T |e verfasserin |4 aut | |
| 700 | 1 | |a Shinji, S |e verfasserin |4 aut | |
| 700 | 1 | |a Shinkawa, H |e verfasserin |4 aut | |
| 700 | 1 | |a Tamura, K |e verfasserin |4 aut | |
| 700 | 1 | |a Uchino, M |e verfasserin |4 aut | |
| 700 | 1 | |a Ohge, H |e verfasserin |4 aut | |
| 700 | 1 | |a Shimizu, J |e verfasserin |4 aut | |
| 700 | 1 | |a Haji, S |e verfasserin |4 aut | |
| 700 | 1 | |a Mohri, Y |e verfasserin |4 aut | |
| 700 | 1 | |a Yamashita, C |e verfasserin |4 aut | |
| 700 | 1 | |a Kitagawa, Y |e verfasserin |4 aut | |
| 700 | 1 | |a Suzuki, K |e verfasserin |4 aut | |
| 700 | 1 | |a Kobayashi, M |e verfasserin |4 aut | |
| 700 | 1 | |a Kobayashi, M |e verfasserin |4 aut | |
| 700 | 1 | |a Hanai, Y |e verfasserin |4 aut | |
| 700 | 1 | |a Nobuhara, H |e verfasserin |4 aut | |
| 700 | 1 | |a Imaoka, H |e verfasserin |4 aut | |
| 700 | 1 | |a Yoshida, M |e verfasserin |4 aut | |
| 700 | 1 | |a Mizuguchi, T |e verfasserin |4 aut | |
| 700 | 1 | |a Mayumi, T |e verfasserin |4 aut | |
| 700 | 1 | |a Kitagawa, Y |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The Journal of hospital infection |d 1993 |g 146(2024) vom: 21. Apr., Seite 174-182 |w (DE-627)NLM012638692 |x 1532-2939 |7 nnns |
| 773 | 1 | 8 | |g volume:146 |g year:2024 |g day:21 |g month:04 |g pages:174-182 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.jhin.2023.09.006 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 146 |j 2024 |b 21 |c 04 |h 174-182 | ||