Impact of diabetes, malnutrition and sarcopenia on the prognosis of patients admitted to internal medicine
Copyright © 2023 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved..
OBJECTIVE: To describe patients hospitalized in internal medicine in terms of malnutrition and sarcopenia, depending on the presence or absence of type 2 diabetes mellitus (DM2), as well as to evaluate short- and long-term mortality related to both.
METHODS: Cross-sectional, single-center study, which included consecutive patients admitted to internal medicine in May and October 2021. Malnutrition was determined using the Mini Nutritional Assessment-Short Form (MNA-SF) and sarcopenia using SARC-F and handgrip strength. Patients hospitalized for more than 48 h are excluded.
RESULTS: 511 patients were analyzed, 49.1% male, mean age 75.2 +/- 15 years, 210 (41.1%) DM2. 6 groups (2 × 3 design) are generated based on the presence of DM2 and the nutritional status according to the result of the MNA-SF: 12-14 points, without risk; MNA-SF 8-12 points, high risk; MNA-SF 0-7 points, malnourished. Malnourished patients with DM2 had significantly higher sarcopenia, comorbidity, inflammation, and pressure ulcers. The main determinants of in-hospital mortality were sarcopenia (OR 1.27, 95%CI 1.06-1.54, p = 0.01), comorbidity (OR 1.27, 95%CI 1,08-1,49, p = 0.003) and inflammation (OR 1.01, 95%CI 1.00-1.02, p = 0.02). The 120-day prognosis was worse among malnourished patients (p = 0.042).
CONCLUSION: Patients admitted with DM2 have a similar degree of malnutrition than the rest, but with greater sarcopenia. This sarcopenia, together with inflammation and comorbidity determine a worse prognosis. The active and early identification of malnutrition and sarcopenia and their subsequent approach could improve the prognosis of patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:223 |
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| Enthalten in: |
Revista clinica espanola - 223(2023), 9 vom: 01. Nov., Seite 523-531 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Galeano-Fernández, T F [VerfasserIn] |
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| Links: |
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| Themen: |
Comorbidity |
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| Anmerkungen: |
Date Completed 06.11.2023 Date Revised 06.11.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.rceng.2023.09.004 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM362135215 |
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| 100 | 1 | |a Galeano-Fernández, T F |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Impact of diabetes, malnutrition and sarcopenia on the prognosis of patients admitted to internal medicine |
| 264 | 1 | |c 2023 | |
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| 500 | |a Date Completed 06.11.2023 | ||
| 500 | |a Date Revised 06.11.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved. | ||
| 520 | |a OBJECTIVE: To describe patients hospitalized in internal medicine in terms of malnutrition and sarcopenia, depending on the presence or absence of type 2 diabetes mellitus (DM2), as well as to evaluate short- and long-term mortality related to both | ||
| 520 | |a METHODS: Cross-sectional, single-center study, which included consecutive patients admitted to internal medicine in May and October 2021. Malnutrition was determined using the Mini Nutritional Assessment-Short Form (MNA-SF) and sarcopenia using SARC-F and handgrip strength. Patients hospitalized for more than 48 h are excluded | ||
| 520 | |a RESULTS: 511 patients were analyzed, 49.1% male, mean age 75.2 +/- 15 years, 210 (41.1%) DM2. 6 groups (2 × 3 design) are generated based on the presence of DM2 and the nutritional status according to the result of the MNA-SF: 12-14 points, without risk; MNA-SF 8-12 points, high risk; MNA-SF 0-7 points, malnourished. Malnourished patients with DM2 had significantly higher sarcopenia, comorbidity, inflammation, and pressure ulcers. The main determinants of in-hospital mortality were sarcopenia (OR 1.27, 95%CI 1.06-1.54, p = 0.01), comorbidity (OR 1.27, 95%CI 1,08-1,49, p = 0.003) and inflammation (OR 1.01, 95%CI 1.00-1.02, p = 0.02). The 120-day prognosis was worse among malnourished patients (p = 0.042) | ||
| 520 | |a CONCLUSION: Patients admitted with DM2 have a similar degree of malnutrition than the rest, but with greater sarcopenia. This sarcopenia, together with inflammation and comorbidity determine a worse prognosis. The active and early identification of malnutrition and sarcopenia and their subsequent approach could improve the prognosis of patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Comorbidity | |
| 650 | 4 | |a Comorbilidad | |
| 650 | 4 | |a Desnutrición | |
| 650 | 4 | |a Diabetes tipo 2 | |
| 650 | 4 | |a Dinamometría | |
| 650 | 4 | |a Dynamometry | |
| 650 | 4 | |a Inflamación | |
| 650 | 4 | |a Inflammation | |
| 650 | 4 | |a Malnutrition | |
| 650 | 4 | |a Sarcopenia | |
| 650 | 4 | |a Type 2 diabetes | |
| 700 | 1 | |a Carretero-Gómez, J |e verfasserin |4 aut | |
| 700 | 1 | |a Vidal-Ríos, A S |e verfasserin |4 aut | |
| 700 | 1 | |a García-García, G M |e verfasserin |4 aut | |
| 700 | 1 | |a García-Carrasco, C |e verfasserin |4 aut | |
| 700 | 1 | |a Monreal-Periañez, F J |e verfasserin |4 aut | |
| 700 | 1 | |a González-González, P |e verfasserin |4 aut | |
| 700 | 1 | |a Córdoba-Bueno, S |e verfasserin |4 aut | |
| 700 | 1 | |a Pijierro-Amador, A |e verfasserin |4 aut | |
| 700 | 1 | |a Carlos Arévalo-Lorido, J |e verfasserin |4 aut | |
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