Safety and efficacy of intraperitoneal drain placement after emergency colorectal surgery : An international, prospective cohort study
© 2023 Association of Coloproctology of Great Britain and Ireland..
AIM: Intraperitoneal drains are often placed during emergency colorectal surgery. However, there is a lack of evidence supporting their use. This study aimed to describe the efficacy and safety of intraperitoneal drain placement after emergency colorectal surgery.
METHOD: COMPlicAted intra-abdominal collectionS after colorectal Surgery (COMPASS) is a prospective, international, cohort study into which consecutive adult patients undergoing emergency colorectal surgery were enrolled (from 3 February 2020 to 8 March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included rate and time-to-diagnosis of postoperative intraperitoneal collections, rate of surgical site infections (SSIs), time to discharge and 30-day major postoperative complications (Clavien-Dindo III-V). Multivariable logistic and Cox proportional hazards regressions were used to estimate the independent association of the outcomes with drain placement.
RESULTS: Some 725 patients (median age 68.0 years; 349 [48.1%] women) from 22 countries were included. The drain insertion rate was 53.7% (389 patients). Following multivariable adjustment, drains were not significantly associated with reduced rates (odds ratio [OR] = 1.56, 95% CI: 0.48-5.02, p = 0.457) or earlier detection (hazard ratio [HR] = 1.07, 95% CI: 0.61-1.90, p = 0.805) of collections. Drains were not significantly associated with worse major postoperative complications (OR = 1.26, 95% CI: 0.67-2.36, p = 0.478), delayed hospital discharge (HR = 1.11, 95% CI: 0.91-1.36, p = 0.303) or increased risk of SSIs (OR = 1.61, 95% CI: 0.87-2.99, p = 0.128).
CONCLUSION: This is the first study investigating placement of intraperitoneal drains following emergency colorectal surgery. The safety and clinical benefit of drains remain uncertain. Equipoise exists for randomized trials to define the safety and efficacy of drains in emergency colorectal surgery.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
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| Enthalten in: |
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 25(2023), 10 vom: 08. Okt., Seite 2043-2053 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
EuroSurg Collaborative† [VerfasserIn] |
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| Links: |
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| Themen: |
Drain |
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| Anmerkungen: |
Date Completed 02.11.2023 Date Revised 10.01.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/codi.16737 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM361978979 |
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| 100 | 0 | |a EuroSurg Collaborative† |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Safety and efficacy of intraperitoneal drain placement after emergency colorectal surgery |b An international, prospective cohort study |
| 264 | 1 | |c 2023 | |
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| 500 | |a Date Completed 02.11.2023 | ||
| 500 | |a Date Revised 10.01.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 Association of Coloproctology of Great Britain and Ireland. | ||
| 520 | |a AIM: Intraperitoneal drains are often placed during emergency colorectal surgery. However, there is a lack of evidence supporting their use. This study aimed to describe the efficacy and safety of intraperitoneal drain placement after emergency colorectal surgery | ||
| 520 | |a METHOD: COMPlicAted intra-abdominal collectionS after colorectal Surgery (COMPASS) is a prospective, international, cohort study into which consecutive adult patients undergoing emergency colorectal surgery were enrolled (from 3 February 2020 to 8 March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included rate and time-to-diagnosis of postoperative intraperitoneal collections, rate of surgical site infections (SSIs), time to discharge and 30-day major postoperative complications (Clavien-Dindo III-V). Multivariable logistic and Cox proportional hazards regressions were used to estimate the independent association of the outcomes with drain placement | ||
| 520 | |a RESULTS: Some 725 patients (median age 68.0 years; 349 [48.1%] women) from 22 countries were included. The drain insertion rate was 53.7% (389 patients). Following multivariable adjustment, drains were not significantly associated with reduced rates (odds ratio [OR] = 1.56, 95% CI: 0.48-5.02, p = 0.457) or earlier detection (hazard ratio [HR] = 1.07, 95% CI: 0.61-1.90, p = 0.805) of collections. Drains were not significantly associated with worse major postoperative complications (OR = 1.26, 95% CI: 0.67-2.36, p = 0.478), delayed hospital discharge (HR = 1.11, 95% CI: 0.91-1.36, p = 0.303) or increased risk of SSIs (OR = 1.61, 95% CI: 0.87-2.99, p = 0.128) | ||
| 520 | |a CONCLUSION: This is the first study investigating placement of intraperitoneal drains following emergency colorectal surgery. The safety and clinical benefit of drains remain uncertain. Equipoise exists for randomized trials to define the safety and efficacy of drains in emergency colorectal surgery | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a drain | |
| 650 | 4 | |a emergency colorectal surgery | |
| 650 | 4 | |a postoperative outcomes | |
| 700 | 1 | |a Sgrò, A |e investigator |4 oth | |
| 700 | 1 | |a Blanco-Colino, R |e investigator |4 oth | |
| 700 | 1 | |a Ahmed, Wur |e investigator |4 oth | |
| 700 | 1 | |a Brindl, N |e investigator |4 oth | |
| 700 | 1 | |a Gujjuri, R R |e investigator |4 oth | |
| 700 | 1 | |a Lapolla, P |e investigator |4 oth | |
| 700 | 1 | |a Mills, E C |e investigator |4 oth | |
| 700 | 1 | |a Pérez-Ajates, S |e investigator |4 oth | |
| 700 | 1 | |a Soares, A S |e investigator |4 oth | |
| 700 | 1 | |a Varghese, C |e investigator |4 oth | |
| 700 | 1 | |a Xu, W |e investigator |4 oth | |
| 700 | 1 | |a McLean, K A |e investigator |4 oth | |
| 700 | 1 | |a Chapman, S J |e investigator |4 oth | |
| 700 | 1 | |a Espín-Basany, E |e investigator |4 oth | |
| 700 | 1 | |a Glasbey, J C |e investigator |4 oth | |
| 700 | 1 | |a Mihaljevic, A |e investigator |4 oth | |
| 700 | 1 | |a Nepogodiev, D |e investigator |4 oth | |
| 700 | 1 | |a Pata, F |e investigator |4 oth | |
| 700 | 1 | |a Pellino, G |e investigator |4 oth | |
| 700 | 1 | |a Pockney, P |e investigator |4 oth | |
| 700 | 1 | |a Dudi-Venkata, N N |e investigator |4 oth | |
| 700 | 1 | |a Egoroff, N |e investigator |4 oth | |
| 700 | 1 | |a Ludbrook, I |e investigator |4 oth | |
| 700 | 1 | |a Raubenheimer, K |e investigator |4 oth | |
| 700 | 1 | |a Richards, T |e investigator |4 oth | |
| 700 | 1 | |a Pockney, P |e investigator |4 oth | |
| 700 | 1 | |a Delibegovic, S |e investigator |4 oth | |
| 700 | 1 | |a Salibasic, M |e investigator |4 oth | |
| 700 | 1 | |a Amjad, T |e investigator |4 oth | |
| 700 | 1 | |a Brindl, N |e investigator |4 oth | |
| 700 | 1 | |a Dörr-Harim, C |e investigator |4 oth | |
| 700 | 1 | |a Gedeon, N |e investigator |4 oth | |
| 700 | 1 | |a Gsenger, J |e investigator |4 oth | |
| 700 | 1 | |a Mihaljevic, A |e investigator |4 oth | |
| 700 | 1 | |a Tachezy, M |e investigator |4 oth | |
| 700 | 1 | |a Bini, S |e investigator |4 oth | |
| 700 | 1 | |a Gallo, G |e investigator |4 oth | |
| 700 | 1 | |a Gori, A |e investigator |4 oth | |
| 700 | 1 | |a Lapolla, P |e investigator |4 oth | |
| 700 | 1 | |a Pata, F |e investigator |4 oth | |
| 700 | 1 | |a Pellino, G |e investigator |4 oth | |
| 700 | 1 | |a Picciariello, A |e investigator |4 oth | |
| 700 | 1 | |a Podda, M |e investigator |4 oth | |
| 700 | 1 | |a Riboni, C |e investigator |4 oth | |
| 700 | 1 | |a Machatschek, M J |e investigator |4 oth | |
| 700 | 1 | |a Nguyen, A |e investigator |4 oth | |
| 700 | 1 | |a Jakubauskas, M |e investigator |4 oth | |
| 700 | 1 | |a Kryzauskas, M |e investigator |4 oth | |
| 700 | 1 | |a Poskus, T |e investigator |4 oth | |
| 700 | 1 | |a Kuiper, S Z |e investigator |4 oth | |
| 700 | 1 | |a Wang, J |e investigator |4 oth | |
| 700 | 1 | |a Wells, C I |e investigator |4 oth | |
| 700 | 1 | |a Bissett, I P |e investigator |4 oth | |
| 700 | 1 | |a Augestad, K M |e investigator |4 oth | |
| 700 | 1 | |a Steinholt, I |e investigator |4 oth | |
| 700 | 1 | |a Soares, A S |e investigator |4 oth | |
| 700 | 1 | |a Vieira, B N |e investigator |4 oth | |
| 700 | 1 | |a Juloski, J |e investigator |4 oth | |
| 700 | 1 | |a Anabitarte Bautista, O |e investigator |4 oth | |
| 700 | 1 | |a Kasmy El Kasmy, Y |e investigator |4 oth | |
| 700 | 1 | |a Pérez-Ajates, S |e investigator |4 oth | |
| 700 | 1 | |a Martín-Borregón, P |e investigator |4 oth | |
| 700 | 1 | |a Ossola Revilla, M |e investigator |4 oth | |
| 700 | 1 | |a Espín-Basany, E |e investigator |4 oth | |
| 700 | 1 | |a Van Straten, S |e investigator |4 oth | |
| 700 | 1 | |a Aktas, M K |e investigator |4 oth | |
| 700 | 1 | |a Baki, B E |e investigator |4 oth | |
| 700 | 1 | |a Ahmed, Wur |e investigator |4 oth | |
| 700 | 1 | |a Akhbari, M |e investigator |4 oth | |
| 700 | 1 | |a Baker, D |e investigator |4 oth | |
| 700 | 1 | |a Bhatia, S |e investigator |4 oth | |
| 700 | 1 | |a Brown, S |e investigator |4 oth | |
| 700 | 1 | |a Cambridge, W |e investigator |4 oth | |
| 700 | 1 | |a Kamarajah, S K |e investigator |4 oth | |
| 700 | 1 | |a Khaw, R A |e investigator |4 oth | |
| 700 | 1 | |a Kouli, O |e investigator |4 oth | |
| 700 | 1 | |a McLean, K A |e investigator |4 oth | |
| 700 | 1 | |a Mills, E C |e investigator |4 oth | |
| 700 | 1 | |a Murray, V |e investigator |4 oth | |
| 700 | 1 | |a Trout, I |e investigator |4 oth | |
| 700 | 1 | |a Yasin, I |e investigator |4 oth | |
| 700 | 1 | |a Wong, J Y |e investigator |4 oth | |
| 700 | 1 | |a Reyhani, H |e investigator |4 oth | |
| 700 | 1 | |a Wong, Khf |e investigator |4 oth | |
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| 700 | 1 | |a Chia, W L |e investigator |4 oth | |
| 700 | 1 | |a Walmsley, A |e investigator |4 oth | |
| 700 | 1 | |a Hassane, A |e investigator |4 oth | |
| 700 | 1 | |a Saeed, D |e investigator |4 oth | |
| 700 | 1 | |a Wang, B |e investigator |4 oth | |
| 700 | 1 | |a Walters, B |e investigator |4 oth | |
| 700 | 1 | |a Nowinka, Z |e investigator |4 oth | |
| 700 | 1 | |a Alsaif, A |e investigator |4 oth | |
| 700 | 1 | |a Mirza, M |e investigator |4 oth | |
| 700 | 1 | |a Foster, K |e investigator |4 oth | |
| 700 | 1 | |a Luu, J |e investigator |4 oth | |
| 700 | 1 | |a Kakodkar, P |e investigator |4 oth | |
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| 700 | 1 | |a Yogarajah, T |e investigator |4 oth | |
| 700 | 1 | |a Antypas, A |e investigator |4 oth | |
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