1,8-cineole (eucalyptol) : A versatile phytochemical with therapeutic applications across multiple diseases

Copyright © 2023 The Authors. Published by Elsevier Masson SAS.. All rights reserved..

1,8-cineole (Eucalyptol), a naturally occurring compound derived from botanical sources such as eucalyptus, rosemary, and camphor laurel, has a long history of use in traditional medicine and exhibits an array of biological properties, including anti-inflammatory, antioxidant, antimicrobial, bronchodilatory, analgesic, and pro-apoptotic effects. Recent evidence has also indicated its potential role in managing conditions such as Alzheimer's disease, neuropathic pain, and cancer. This review spotlights the health advantages of 1,8-cineole, as demonstrated in clinical trials involving patients with respiratory disorders, including chronic obstructive pulmonary disease, asthma, bronchitis, and rhinosinusitis. In addition, we shed light on potential therapeutic applications of 1,8-cineole in various conditions, such as depression, epilepsy, peptic ulcer disease, diarrhea, cardiac-related heart diseases, and diabetes mellitus. A comprehensive understanding of 1,8-cineole's pharmacodynamics and safety aspects as well as developing effective formulations, might help to leverage its therapeutic value. This thorough review sets the stage for future research on diverse health benefits and potential uses of 1,8-cineole in tackling complex medical conditions.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:167

Enthalten in:

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 167(2023) vom: 01. Nov., Seite 115467

Sprache:

Englisch

Beteiligte Personen:

Hoch, Cosima C [VerfasserIn]
Petry, Julie [VerfasserIn]
Griesbaum, Lena [VerfasserIn]
Weiser, Tobias [VerfasserIn]
Werner, Kathrin [VerfasserIn]
Ploch, Michael [VerfasserIn]
Verschoor, Admar [VerfasserIn]
Multhoff, Gabriele [VerfasserIn]
Bashiri Dezfouli, Ali [VerfasserIn]
Wollenberg, Barbara [VerfasserIn]

Links:

Volltext

Themen:

1,8-cineole
Anti-inflammatory activity
Antimicrobial
Antioxidant
Eucalyptol
Journal Article
Respiratory disorders
Review

Anmerkungen:

Date Revised 17.10.2023

published: Print-Electronic

Citation Status Publisher

doi:

10.1016/j.biopha.2023.115467

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM361935145