Long-Term Outcomes of Pylorus-Preserving Gastrectomy for Early Gastric Cancer

BACKGROUND: In the short term, pylorus-preserving gastrectomy (PPG) has been reported to have advantages over distal gastrectomy (DG) with regard to postprandial symptoms and dumping syndrome. We aimed to evaluate the quality of life after PPG for early gastric cancer in the long term in comparison to that after DG.

METHODS: Twenty-six patients who underwent gastrectomy (11 PPG, 15 DG) for early gastric cancer at Osaka University Hospital participated and were followed for more than 4 years. Body weight changes, nutritional status, dual-phase scintigraphy findings, endoscopic survey results, and questionnaire responses after gastrectomy were examined.

RESULTS: There were significantly lower ratios of weight changes in PPG than in DG, 5 years after surgery. There were no differences in the clinicopathological characteristics, nutritional parameters, questionnaire responses, and endoscopic findings between the two groups. Based on gastric scintigraphy, although the gastric emptying of liquids showed similar curves in the two groups, gastric emptying of solids was significantly slower in the PPG group than in the DG group (P = .039).

DISCUSSION: PPG had advantages with regard to long-term outcomes over DG in terms of weight maintenance and the prevention of rapid gastric emptying. PPG might be efficient in patients with early gastric cancer.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:90

Enthalten in:

The American surgeon - 90(2024), 3 vom: 15. Feb., Seite 386-392

Sprache:

Englisch

Beteiligte Personen:

Saito, Yurina [VerfasserIn]
Takahashi, Tsuyoshi [VerfasserIn]
Nishida, Toshirou [VerfasserIn]
Murakami, Kohei [VerfasserIn]
Endo, Shunji [VerfasserIn]
Nishikawa, Kazuhiro [VerfasserIn]
Kimura, Yutaka [VerfasserIn]
Motoori, Masaaki [VerfasserIn]
Tanaka, Koji [VerfasserIn]
Miyazaki, Yasuhiro [VerfasserIn]
Makino, Tomoki [VerfasserIn]
Kurokawa, Yukinori [VerfasserIn]
Yamasaki, Makoto [VerfasserIn]
Nakajima, Kiyokazu [VerfasserIn]
Eguchi, Hidetoshi [VerfasserIn]
Doki, Yuichiro [VerfasserIn]

Links:

Volltext

Themen:

Early gastric cancer
Journal Article
PPG
Pylorus-preserving

Anmerkungen:

Date Completed 14.02.2024

Date Revised 14.02.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/00031348231200671

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM361859694