A proposed framework for advancing acute kidney injury risk stratification and diagnosis in children : a report from the 26th Acute Disease Quality Initiative (ADQI) conference
© 2023. The Author(s)..
Acute kidney injury (AKI) in children is associated with increased morbidity, reduced health-related quality of life, greater resource utilization, and higher mortality. Improvements in the timeliness and precision of AKI diagnosis in children are needed. In this report, we highlight existing, novel, and on-the-horizon diagnostic and risk-stratification tools for pediatric AKI, and outline opportunities for integration into clinical practice. We also summarize pediatric-specific high-risk diagnoses and exposures for AKI, as well as the potential role of real-time risk stratification and clinical decision support to improve outcomes. Lastly, the key characteristics of important pediatric AKI phenotypes will be outlined. Throughout, we identify key knowledge gaps, which represent prioritized areas of focus for future research that will facilitate a comprehensive, timely and personalized approach to pediatric AKI diagnosis and management.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:39 |
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| Enthalten in: |
Pediatric nephrology (Berlin, Germany) - 39(2024), 3 vom: 31. März, Seite 929-939 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Fuhrman, Dana Y [VerfasserIn] |
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| Links: |
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| Themen: |
Acute kidney injury |
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| Anmerkungen: |
Date Completed 29.01.2024 Date Revised 10.04.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00467-023-06133-3 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM361677464 |
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| 245 | 1 | 2 | |a A proposed framework for advancing acute kidney injury risk stratification and diagnosis in children |b a report from the 26th Acute Disease Quality Initiative (ADQI) conference |
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| 500 | |a Date Completed 29.01.2024 | ||
| 500 | |a Date Revised 10.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023. The Author(s). | ||
| 520 | |a Acute kidney injury (AKI) in children is associated with increased morbidity, reduced health-related quality of life, greater resource utilization, and higher mortality. Improvements in the timeliness and precision of AKI diagnosis in children are needed. In this report, we highlight existing, novel, and on-the-horizon diagnostic and risk-stratification tools for pediatric AKI, and outline opportunities for integration into clinical practice. We also summarize pediatric-specific high-risk diagnoses and exposures for AKI, as well as the potential role of real-time risk stratification and clinical decision support to improve outcomes. Lastly, the key characteristics of important pediatric AKI phenotypes will be outlined. Throughout, we identify key knowledge gaps, which represent prioritized areas of focus for future research that will facilitate a comprehensive, timely and personalized approach to pediatric AKI diagnosis and management | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Acute kidney injury | |
| 650 | 4 | |a Biomarkers | |
| 650 | 4 | |a Diagnosis | |
| 650 | 4 | |a Pediatrics | |
| 650 | 4 | |a Phenotypes | |
| 650 | 4 | |a Precision medicine | |
| 650 | 7 | |a Biomarkers |2 NLM | |
| 700 | 1 | |a Stanski, Natalja L |e verfasserin |4 aut | |
| 700 | 1 | |a Krawczeski, Catherine D |e verfasserin |4 aut | |
| 700 | 1 | |a Greenberg, Jason H |e verfasserin |4 aut | |
| 700 | 1 | |a Arikan, A Ayse Akcan |e verfasserin |4 aut | |
| 700 | 1 | |a Basu, Raj K |e verfasserin |4 aut | |
| 700 | 1 | |a Goldstein, Stuart L |e verfasserin |4 aut | |
| 700 | 1 | |a Gist, Katja M |e verfasserin |4 aut | |
| 700 | 0 | |a ADQI 26 workgroup |e verfasserin |4 aut | |
| 700 | 1 | |a Alobaidi, Rashid |e investigator |4 oth | |
| 700 | 1 | |a Askenazi, David J |e investigator |4 oth | |
| 700 | 1 | |a Bagshaw, Sean M |e investigator |4 oth | |
| 700 | 1 | |a Barhight, Matthew |e investigator |4 oth | |
| 700 | 1 | |a Barreto, Erin |e investigator |4 oth | |
| 700 | 1 | |a Bayrakci, Benan |e investigator |4 oth | |
| 700 | 1 | |a Ray Bignall, O N |c 2nd |e investigator |4 oth | |
| 700 | 1 | |a Bjornstad, Erica |e investigator |4 oth | |
| 700 | 1 | |a Brophy, Patrick |e investigator |4 oth | |
| 700 | 1 | |a Charlton, Jennifer |e investigator |4 oth | |
| 700 | 1 | |a Chanchlani, Rahul |e investigator |4 oth | |
| 700 | 1 | |a Conroy, Andrea L |e investigator |4 oth | |
| 700 | 1 | |a Deep, Akash |e investigator |4 oth | |
| 700 | 1 | |a Devarajan, Prasad |e investigator |4 oth | |
| 700 | 1 | |a Dolan, Kristin |e investigator |4 oth | |
| 700 | 1 | |a Fuhrman, Dana |e investigator |4 oth | |
| 700 | 1 | |a Gist, Katja M |e investigator |4 oth | |
| 700 | 1 | |a Gorga, Stephen M |e investigator |4 oth | |
| 700 | 1 | |a Greenberg, Jason H |e investigator |4 oth | |
| 700 | 1 | |a Hasson, Denise |e investigator |4 oth | |
| 700 | 1 | |a Heydari, Emma |e investigator |4 oth | |
| 700 | 1 | |a Iyengar, Arpana |e investigator |4 oth | |
| 700 | 1 | |a Jetton, Jennifer |e investigator |4 oth | |
| 700 | 1 | |a Krawczeski, Catherine |e investigator |4 oth | |
| 700 | 1 | |a Meigs, Leslie |e investigator |4 oth | |
| 700 | 1 | |a Menon, Shina |e investigator |4 oth | |
| 700 | 1 | |a Morgan, Catherine |e investigator |4 oth | |
| 700 | 1 | |a Morgan, Jolyn |e investigator |4 oth | |
| 700 | 1 | |a Mottes, Theresa |e investigator |4 oth | |
| 700 | 1 | |a Neumayr, Tara |e investigator |4 oth | |
| 700 | 1 | |a Ricci, Zaccaria |e investigator |4 oth | |
| 700 | 1 | |a Selewski, David T |e investigator |4 oth | |
| 700 | 1 | |a Soranno, Danielle |e investigator |4 oth | |
| 700 | 1 | |a Stanski, Natalja |e investigator |4 oth | |
| 700 | 1 | |a Starr, Michelle |e investigator |4 oth | |
| 700 | 1 | |a Sutherland, Scott M |e investigator |4 oth | |
| 700 | 1 | |a Symons, Jordan |e investigator |4 oth | |
| 700 | 1 | |a Tavares, Marcelo |e investigator |4 oth | |
| 700 | 1 | |a Vega, Molly |e investigator |4 oth | |
| 700 | 1 | |a Zappitelli, Michael |e investigator |4 oth | |
| 700 | 1 | |a Ronco, Claudio |e investigator |4 oth | |
| 700 | 1 | |a Mehta, Ravindra L |e investigator |4 oth | |
| 700 | 1 | |a Kellum, John |e investigator |4 oth | |
| 700 | 1 | |a Ostermann, Marlies |e investigator |4 oth | |
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