Systematic influenza screening in cardiac intensive care units during the influenza season : A prospective study in Spain
Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved..
BACKGROUND: Little is known about the incidence of influenza among admissions to the cardiac intensive care unit (C-ICU), accuracy of clinical suspicion, and influenza vaccination uptake. We evaluated the incidence of influenza at C-ICU admission during the influenza season, potential underdiagnosis, and vaccination uptake.
METHODS: Prospective study at five C-ICUs during the 2017-2020 influenza seasons. A nasopharyngeal swab was collected at admission from patients who consented (n = 788). Testing was with Xpert®XpressFlu/RSV.
RESULTS: Influenza was detected in 43 patients (5.5%) (40 FluA; 3 FluB) and clinically suspected in 27 (62.8%). Compared to patients without influenza, patients with influenza more frequently had heart failure (37.2% vs 22.8%, P = 0.031), previous contact with relatives with influenza-like illnesses (23.3% vs 12.5%, P = 0.042), antimicrobial use (67.4% vs 23.2%, P <0.01), and need for mechanical ventilation (25.6% vs 14.5%, P = 0.048). Patients received oseltamivir promptly. We found no differences in mortality (11.6% vs 5.2%, P = 0.076). Patients with influenza more frequently had myocarditis (9.3% vs 0.9%, P <0.01) and pericarditis (7.0% vs 0.8%, P = 0.01). Overall, 43.0% of patients (339/788) were vaccinated (51.9% of those with a clear indication [303/584]).
CONCLUSION: Influenza seems to be a frequently underdiagnosed underlying condition in admissions to the C-ICU. Influenza should be screened for at C-ICU admission during influenza epidemics.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:136 |
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| Enthalten in: |
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 136(2023) vom: 03. Nov., Seite 37-42 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Galar, Alicia [VerfasserIn] |
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| Links: |
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| Themen: |
Acute cardiac events |
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| Anmerkungen: |
Date Completed 27.10.2023 Date Revised 12.11.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ijid.2023.08.027 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM361673914 |
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| 100 | 1 | |a Galar, Alicia |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Systematic influenza screening in cardiac intensive care units during the influenza season |b A prospective study in Spain |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Completed 27.10.2023 | ||
| 500 | |a Date Revised 12.11.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved. | ||
| 520 | |a BACKGROUND: Little is known about the incidence of influenza among admissions to the cardiac intensive care unit (C-ICU), accuracy of clinical suspicion, and influenza vaccination uptake. We evaluated the incidence of influenza at C-ICU admission during the influenza season, potential underdiagnosis, and vaccination uptake | ||
| 520 | |a METHODS: Prospective study at five C-ICUs during the 2017-2020 influenza seasons. A nasopharyngeal swab was collected at admission from patients who consented (n = 788). Testing was with Xpert®XpressFlu/RSV | ||
| 520 | |a RESULTS: Influenza was detected in 43 patients (5.5%) (40 FluA; 3 FluB) and clinically suspected in 27 (62.8%). Compared to patients without influenza, patients with influenza more frequently had heart failure (37.2% vs 22.8%, P = 0.031), previous contact with relatives with influenza-like illnesses (23.3% vs 12.5%, P = 0.042), antimicrobial use (67.4% vs 23.2%, P <0.01), and need for mechanical ventilation (25.6% vs 14.5%, P = 0.048). Patients received oseltamivir promptly. We found no differences in mortality (11.6% vs 5.2%, P = 0.076). Patients with influenza more frequently had myocarditis (9.3% vs 0.9%, P <0.01) and pericarditis (7.0% vs 0.8%, P = 0.01). Overall, 43.0% of patients (339/788) were vaccinated (51.9% of those with a clear indication [303/584]) | ||
| 520 | |a CONCLUSION: Influenza seems to be a frequently underdiagnosed underlying condition in admissions to the C-ICU. Influenza should be screened for at C-ICU admission during influenza epidemics | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Acute cardiac events | |
| 650 | 4 | |a Influenza | |
| 650 | 4 | |a Systematic screening | |
| 700 | 1 | |a Juárez, Miriam |e verfasserin |4 aut | |
| 700 | 1 | |a Sousa-Casasnovas, Iago |e verfasserin |4 aut | |
| 700 | 1 | |a Catalán, Pilar |e verfasserin |4 aut | |
| 700 | 1 | |a Valerio, Maricela |e verfasserin |4 aut | |
| 700 | 1 | |a Antunez-Muiños, Pablo |e verfasserin |4 aut | |
| 700 | 1 | |a Barbeito-Castiñeiras, Gema |e verfasserin |4 aut | |
| 700 | 1 | |a Blanco-Alonso, Silvia |e verfasserin |4 aut | |
| 700 | 1 | |a Folgueira, María Dolores |e verfasserin |4 aut | |
| 700 | 1 | |a García-Acuña, José María |e verfasserin |4 aut | |
| 700 | 1 | |a Lalueza, Antonio |e verfasserin |4 aut | |
| 700 | 1 | |a Lázaro-Perona, Fernando |e verfasserin |4 aut | |
| 700 | 1 | |a López de Sá, Esteban |e verfasserin |4 aut | |
| 700 | 1 | |a Martín, Lorena |e verfasserin |4 aut | |
| 700 | 1 | |a Muñez, Elena |e verfasserin |4 aut | |
| 700 | 1 | |a Portero, Francisca |e verfasserin |4 aut | |
| 700 | 1 | |a Ramos-Martínez, Antonio |e verfasserin |4 aut | |
| 700 | 1 | |a Romero-Gómez, María Pilar |e verfasserin |4 aut | |
| 700 | 1 | |a Rosillo, Sandra |e verfasserin |4 aut | |
| 700 | 1 | |a Fernández-Avilés, Francisco |e verfasserin |4 aut | |
| 700 | 1 | |a Martínez-Sellés, Manuel |e verfasserin |4 aut | |
| 700 | 1 | |a Bouza, Emilio |e verfasserin |4 aut | |
| 700 | 1 | |a Muñoz, Patricia |e verfasserin |4 aut | |
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