Research progress on desensitization of hypersensitivity reaction to iodinated contrast media
Desensitization therapy for iodinated contrast media (ICM) aims to induce drug tolerance in patients with a history of severe allergic reactions to ICM in a short time. Currently, there is no widely accepted consensus on inducing desensitization to avoid severe allergic responses to ICM. The clinically successful cases have shown that prophylactic use of antihistamines and glucocorticoids can increase the desensitization effect; repeatedly desensitizing and gradually increasing the dose can be conducive to establishing better tolerance to ICM. Most desensitization effects, including stress resistance, can endure 24-48 h. The mechanisms of desensitization therapy remain unclear, the initial dose, administration interval and dose gradient are largely based on clinical experiences and the reaction of patients. This article reviews the current research progress on ICM-related allergies, desensitization methods and related mechanisms, as well as the benefits and hazards of desensitization, to provide a reference for desensitization treatment of hypersensitivity to ICM.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:52 |
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| Enthalten in: |
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 52(2023), 4 vom: 25. Aug., Seite 526-530 |
| Sprache: |
Englisch |
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| Weiterer Titel: |
碘造影剂超敏反应患者脱敏治疗的研究进展 |
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| Beteiligte Personen: |
Fan, Miao [VerfasserIn] |
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| Links: |
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| Themen: |
Contrast Media |
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| Anmerkungen: |
Date Completed 31.08.2023 Date Revised 15.11.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.3724/zdxbyxb-2023-0220 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM361418906 |
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| 245 | 1 | 0 | |a Research progress on desensitization of hypersensitivity reaction to iodinated contrast media |
| 246 | 3 | 3 | |a 碘造影剂超敏反应患者脱敏治疗的研究进展 |
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| 520 | |a Desensitization therapy for iodinated contrast media (ICM) aims to induce drug tolerance in patients with a history of severe allergic reactions to ICM in a short time. Currently, there is no widely accepted consensus on inducing desensitization to avoid severe allergic responses to ICM. The clinically successful cases have shown that prophylactic use of antihistamines and glucocorticoids can increase the desensitization effect; repeatedly desensitizing and gradually increasing the dose can be conducive to establishing better tolerance to ICM. Most desensitization effects, including stress resistance, can endure 24-48 h. The mechanisms of desensitization therapy remain unclear, the initial dose, administration interval and dose gradient are largely based on clinical experiences and the reaction of patients. This article reviews the current research progress on ICM-related allergies, desensitization methods and related mechanisms, as well as the benefits and hazards of desensitization, to provide a reference for desensitization treatment of hypersensitivity to ICM | ||
| 650 | 4 | |a Review | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Desensitization therapy | |
| 650 | 4 | |a Effective duration | |
| 650 | 4 | |a Hypersensitive | |
| 650 | 4 | |a Iodinated contrast media | |
| 650 | 4 | |a Mechanism | |
| 650 | 4 | |a Regimen | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a Contrast Media |2 NLM | |
| 650 | 7 | |a Glucocorticoids |2 NLM | |
| 700 | 1 | |a Zheng, Xiaomeng |e verfasserin |4 aut | |
| 700 | 1 | |a Zhu, Suyan |e verfasserin |4 aut | |
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