Nickel-Catalyzed Reductive Cross-Coupling of Aziridines and Allylic Chlorides
A nickel-catalyzed reductive cross-coupling of aziridines and allylic chlorides was realized by using manganese metal as the reducing agent. This protocol afforded a convenient approach to obtain β-allyl-substituted arylethylamines bearing various functional groups. The utility of this reaction was also demonstrated by scale-up preparation and diverse transformations, including the synthesis of Baclofen and several bioactive molecular motifs.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
|---|---|
| Enthalten in: |
Organic letters - 25(2023), 35 vom: 08. Sept., Seite 6582-6586 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Liu, Shuai [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Revised 08.09.2023 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.1021/acs.orglett.3c02399 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM361403283 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM361403283 | ||
| 003 | DE-627 | ||
| 005 | 20231226085050.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1021/acs.orglett.3c02399 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1204.xml |
| 035 | |a (DE-627)NLM361403283 | ||
| 035 | |a (NLM)37642345 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Liu, Shuai |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Nickel-Catalyzed Reductive Cross-Coupling of Aziridines and Allylic Chlorides |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 08.09.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a A nickel-catalyzed reductive cross-coupling of aziridines and allylic chlorides was realized by using manganese metal as the reducing agent. This protocol afforded a convenient approach to obtain β-allyl-substituted arylethylamines bearing various functional groups. The utility of this reaction was also demonstrated by scale-up preparation and diverse transformations, including the synthesis of Baclofen and several bioactive molecular motifs | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Wang, Sen-Lin |e verfasserin |4 aut | |
| 700 | 1 | |a Wan, Jie |e verfasserin |4 aut | |
| 700 | 1 | |a Peng, Shuang |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Jie-Rui |e verfasserin |4 aut | |
| 700 | 1 | |a Ding, Hua-Jiao |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Bin |e verfasserin |4 aut | |
| 700 | 1 | |a Ni, Hai-Liang |e verfasserin |4 aut | |
| 700 | 1 | |a Cao, Peng |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, Ping |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Bi-Qin |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Bin |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Organic letters |d 1999 |g 25(2023), 35 vom: 08. Sept., Seite 6582-6586 |w (DE-627)NLM106817639 |x 1523-7052 |7 nnns |
| 773 | 1 | 8 | |g volume:25 |g year:2023 |g number:35 |g day:08 |g month:09 |g pages:6582-6586 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1021/acs.orglett.3c02399 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 25 |j 2023 |e 35 |b 08 |c 09 |h 6582-6586 | ||