Liver Re-transplantation in Adults : Indications and Outcomes Analysis of a 23-year Experience in a Single Center in Argentina
Background: Liver re-transplantation (re-LT) represents the only treatment for patients with irreversible graft failure.
Objective: The aim of the current study was to describe the outcomes of both, patient and graft, after re- LT, at a high-volume referral center.
Methods: Our population consisted of patients, with liver disease, who underwent re-LT in our institution between January 1996 and December 2019.
Results: 49 patients met the inclusion criteria. The patient's overall survival (OS) for the first year was 85% (Confidence Intervals (CI) 71-92) and 70% at five years (CI 53-82). In our population, three (6.12%) patients presented loss of graft and were included again in the transplant list; of these, one agreed to a new transplant while the remaining two died. This gave us graft survival results similar to those obtained for the re-LT patient; 85% at one year (CI 71-92) and 70% at 5 years (CI 53-82).
Conclusion: Our study shows that re-LT is a valid and safe treatment for both early graft dysfunction and for transplanted patients who again present end-stage liver disease, showing a satisfactory long-term evolution, with parameters comparable to primary transplantation.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
International journal of organ transplantation medicine - 13(2022), 2 vom: 29., Seite 30-35 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bruballa, R [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Revised 29.08.2023 published: Print Citation Status PubMed-not-MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM36139716X |
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| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
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| 041 | |a eng | ||
| 100 | 1 | |a Bruballa, R |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Liver Re-transplantation in Adults |b Indications and Outcomes Analysis of a 23-year Experience in a Single Center in Argentina |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Revised 29.08.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Background: Liver re-transplantation (re-LT) represents the only treatment for patients with irreversible graft failure | ||
| 520 | |a Objective: The aim of the current study was to describe the outcomes of both, patient and graft, after re- LT, at a high-volume referral center | ||
| 520 | |a Methods: Our population consisted of patients, with liver disease, who underwent re-LT in our institution between January 1996 and December 2019 | ||
| 520 | |a Results: 49 patients met the inclusion criteria. The patient's overall survival (OS) for the first year was 85% (Confidence Intervals (CI) 71-92) and 70% at five years (CI 53-82). In our population, three (6.12%) patients presented loss of graft and were included again in the transplant list; of these, one agreed to a new transplant while the remaining two died. This gave us graft survival results similar to those obtained for the re-LT patient; 85% at one year (CI 71-92) and 70% at 5 years (CI 53-82) | ||
| 520 | |a Conclusion: Our study shows that re-LT is a valid and safe treatment for both early graft dysfunction and for transplanted patients who again present end-stage liver disease, showing a satisfactory long-term evolution, with parameters comparable to primary transplantation | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Liver disease | |
| 650 | 4 | |a Liver transplantation | |
| 650 | 4 | |a Surgery | |
| 700 | 1 | |a Sanchez Thomas, D |e verfasserin |4 aut | |
| 700 | 1 | |a de Santl'banes, E |e verfasserin |4 aut | |
| 700 | 1 | |a Ciardullo, M |e verfasserin |4 aut | |
| 700 | 1 | |a Mattera, J |e verfasserin |4 aut | |
| 700 | 1 | |a Pekolj, J |e verfasserin |4 aut | |
| 700 | 1 | |a de Santibanes, M |e verfasserin |4 aut | |
| 700 | 1 | |a Ardiles, V |e verfasserin |4 aut | |
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