Mitral annular plane systolic excursion for assessing left ventricular systolic dysfunction in patients with septic shock
© 2023 The Authors..
Background: Using easy-to-determine bedside measurements, we developed an echocardiographic algorithm for predicting left ventricular ejection fraction (LVEF) and longitudinal strain (LVLS) in patients with septic shock.
Methods: We measured septal and lateral mitral annular plane systolic excursion (MAPSE), septal and lateral mitral S-wave velocity, and the left ventricular longitudinal wall fractional shortening in patients with septic shock. We used a conditional inference tree method to build a stratification algorithm. The left ventricular systolic dysfunction was defined as an LVEF <50%, an LVLS greater than -17%, or both.
Results: We included 71 patients (males: 61%; mean [standard deviation] age: 61 [15] yr). Septal MAPSE (cut-off: 1.2 cm) was the best predictor of left ventricular systolic dysfunction. The level of agreement between the septal MAPSE and the left ventricular systolic dysfunction was 0.525 [0.299-0.751]. A septal MAPSE ≥1.2 cm predicted normal LVEF in 17/18 patients, or 94%. In contrast, a septal MAPSE <1.2 cm predicted left ventricular systolic dysfunction with impaired LVLS in 46/53 patients (87%), although 32/53 (60%) patients had a preserved LVEF.
Conclusions: Septal MAPSE is easily measured at the bedside and might help clinicians to detect left ventricular systolic dysfunction early-especially when myocardial strain measurements are not feasible.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:7 |
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| Enthalten in: |
BJA open - 7(2023) vom: 22. Sept., Seite 100220 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Brault, Clément [VerfasserIn] |
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| Links: |
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| Themen: |
Global longitudinal strain |
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| Anmerkungen: |
Date Revised 29.08.2023 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.bjao.2023.100220 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM361362099 |
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| 245 | 1 | 0 | |a Mitral annular plane systolic excursion for assessing left ventricular systolic dysfunction in patients with septic shock |
| 264 | 1 | |c 2023 | |
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| 500 | |a Date Revised 29.08.2023 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2023 The Authors. | ||
| 520 | |a Background: Using easy-to-determine bedside measurements, we developed an echocardiographic algorithm for predicting left ventricular ejection fraction (LVEF) and longitudinal strain (LVLS) in patients with septic shock | ||
| 520 | |a Methods: We measured septal and lateral mitral annular plane systolic excursion (MAPSE), septal and lateral mitral S-wave velocity, and the left ventricular longitudinal wall fractional shortening in patients with septic shock. We used a conditional inference tree method to build a stratification algorithm. The left ventricular systolic dysfunction was defined as an LVEF <50%, an LVLS greater than -17%, or both | ||
| 520 | |a Results: We included 71 patients (males: 61%; mean [standard deviation] age: 61 [15] yr). Septal MAPSE (cut-off: 1.2 cm) was the best predictor of left ventricular systolic dysfunction. The level of agreement between the septal MAPSE and the left ventricular systolic dysfunction was 0.525 [0.299-0.751]. A septal MAPSE ≥1.2 cm predicted normal LVEF in 17/18 patients, or 94%. In contrast, a septal MAPSE <1.2 cm predicted left ventricular systolic dysfunction with impaired LVLS in 46/53 patients (87%), although 32/53 (60%) patients had a preserved LVEF | ||
| 520 | |a Conclusions: Septal MAPSE is easily measured at the bedside and might help clinicians to detect left ventricular systolic dysfunction early-especially when myocardial strain measurements are not feasible | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a global longitudinal strain | |
| 650 | 4 | |a left ventricular ejection fraction | |
| 650 | 4 | |a mitral annular plane systolic excursion | |
| 650 | 4 | |a septic cardiomyopathy | |
| 650 | 4 | |a septic shock | |
| 700 | 1 | |a Zerbib, Yoann |e verfasserin |4 aut | |
| 700 | 1 | |a Mercado, Pablo |e verfasserin |4 aut | |
| 700 | 1 | |a Diouf, Momar |e verfasserin |4 aut | |
| 700 | 1 | |a Michaud, Audrey |e verfasserin |4 aut | |
| 700 | 1 | |a Tribouilloy, Christophe |e verfasserin |4 aut | |
| 700 | 1 | |a Maizel, Julien |e verfasserin |4 aut | |
| 700 | 1 | |a Slama, Michel |e verfasserin |4 aut | |
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