Antidiabetic Effect of Star Anise (Illicium verum) in Streptozotocin-induced Diabetic Rats
Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net..
AIM: The current study aimed to evaluate the antidiabetic potential of Illicium verum fruits.
BACKGROUND: Illicium verum fruits are frequently used by the Moroccan population in the treatment of diabetes.
METHODS: The antihyperglycemic effect of the aqueous extract of Illicium verum fruits (AEIVF) in rats was assessed. The effects of AEIVF (20 mg/kg) on glycemia and lipid profile as well as its phytochemical and antioxidant properties were evaluated.
RESULTS: In normal and diabetic rats, AEIVF reduced blood glucose levels 6 hours after administration. Furthermore, after 7 days of treatment, glycemia was lowered in diabetic rats, and this extract exhibited an antioxidant activity.
CONCLUSION: The study shows that Illicium verum possesses a potent antidiabetic activity. In addition, the toxicity of AEIVF was evaluated and the LD50 value was found to be greater than the 2 g/kg dose.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:23 |
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| Enthalten in: |
Cardiovascular & hematological disorders drug targets - 23(2023), 2 vom: 24., Seite 92-98 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Amtaghri, Smail [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 16.12.2023 Date Revised 20.03.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.2174/1871529X23666230823112113 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM361112793 |
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| 500 | |a Date Completed 16.12.2023 | ||
| 500 | |a Date Revised 20.03.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net. | ||
| 520 | |a AIM: The current study aimed to evaluate the antidiabetic potential of Illicium verum fruits | ||
| 520 | |a BACKGROUND: Illicium verum fruits are frequently used by the Moroccan population in the treatment of diabetes | ||
| 520 | |a METHODS: The antihyperglycemic effect of the aqueous extract of Illicium verum fruits (AEIVF) in rats was assessed. The effects of AEIVF (20 mg/kg) on glycemia and lipid profile as well as its phytochemical and antioxidant properties were evaluated | ||
| 520 | |a RESULTS: In normal and diabetic rats, AEIVF reduced blood glucose levels 6 hours after administration. Furthermore, after 7 days of treatment, glycemia was lowered in diabetic rats, and this extract exhibited an antioxidant activity | ||
| 520 | |a CONCLUSION: The study shows that Illicium verum possesses a potent antidiabetic activity. In addition, the toxicity of AEIVF was evaluated and the LD50 value was found to be greater than the 2 g/kg dose | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Illicium verum | |
| 650 | 4 | |a antidiabetic | |
| 650 | 4 | |a antioxidant activity | |
| 650 | 4 | |a oral glucose test tolerance | |
| 650 | 4 | |a phytochemical | |
| 650 | 4 | |a streptozotocin | |
| 650 | 4 | |a toxicity. | |
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| 650 | 7 | |a Plant Extracts |2 NLM | |
| 650 | 7 | |a Antioxidants |2 NLM | |
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| 700 | 1 | |a Slaoui, Miloudia |e verfasserin |4 aut | |
| 700 | 1 | |a Eddouks, Mohamed |e verfasserin |4 aut | |
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