Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience : A Review
Importance: Climate change, pollution, urbanization, socioeconomic inequality, and psychosocial effects of the COVID-19 pandemic have caused massive changes in environmental conditions that affect brain health during the life span, both on a population level as well as on the level of the individual. How these environmental factors influence the brain, behavior, and mental illness is not well known.
Observations: A research strategy enabling population neuroscience to contribute to identify brain mechanisms underlying environment-related mental illness by leveraging innovative enrichment tools for data federation, geospatial observation, climate and pollution measures, digital health, and novel data integration techniques is described. This strategy can inform innovative treatments that target causal cognitive and molecular mechanisms of mental illness related to the environment. An example is presented of the environMENTAL Project that is leveraging federated cohort data of over 1.5 million European citizens and patients enriched with deep phenotyping data from large-scale behavioral neuroimaging cohorts to identify brain mechanisms related to environmental adversity underlying symptoms of depression, anxiety, stress, and substance misuse.
Conclusions and Relevance: This research will lead to the development of objective biomarkers and evidence-based interventions that will significantly improve outcomes of environment-related mental illness.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:80 |
|---|---|
| Enthalten in: |
JAMA psychiatry - 80(2023), 10 vom: 01. Okt., Seite 1066-1074 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Schumann, Gunter [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 05.10.2023 Date Revised 20.03.2024 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1001/jamapsychiatry.2023.2996 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM361091877 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM361091877 | ||
| 003 | DE-627 | ||
| 005 | 20240320233352.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1001/jamapsychiatry.2023.2996 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1337.xml |
| 035 | |a (DE-627)NLM361091877 | ||
| 035 | |a (NLM)37610741 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Schumann, Gunter |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience |b A Review |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 05.10.2023 | ||
| 500 | |a Date Revised 20.03.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Importance: Climate change, pollution, urbanization, socioeconomic inequality, and psychosocial effects of the COVID-19 pandemic have caused massive changes in environmental conditions that affect brain health during the life span, both on a population level as well as on the level of the individual. How these environmental factors influence the brain, behavior, and mental illness is not well known | ||
| 520 | |a Observations: A research strategy enabling population neuroscience to contribute to identify brain mechanisms underlying environment-related mental illness by leveraging innovative enrichment tools for data federation, geospatial observation, climate and pollution measures, digital health, and novel data integration techniques is described. This strategy can inform innovative treatments that target causal cognitive and molecular mechanisms of mental illness related to the environment. An example is presented of the environMENTAL Project that is leveraging federated cohort data of over 1.5 million European citizens and patients enriched with deep phenotyping data from large-scale behavioral neuroimaging cohorts to identify brain mechanisms related to environmental adversity underlying symptoms of depression, anxiety, stress, and substance misuse | ||
| 520 | |a Conclusions and Relevance: This research will lead to the development of objective biomarkers and evidence-based interventions that will significantly improve outcomes of environment-related mental illness | ||
| 650 | 4 | |a Review | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 700 | 1 | |a Andreassen, Ole A |e verfasserin |4 aut | |
| 700 | 1 | |a Banaschewski, Tobias |e verfasserin |4 aut | |
| 700 | 1 | |a Calhoun, Vince D |e verfasserin |4 aut | |
| 700 | 1 | |a Clinton, Nicholas |e verfasserin |4 aut | |
| 700 | 1 | |a Desrivieres, Sylvane |e verfasserin |4 aut | |
| 700 | 1 | |a Brandlistuen, Ragnhild Eek |e verfasserin |4 aut | |
| 700 | 1 | |a Feng, Jianfeng |e verfasserin |4 aut | |
| 700 | 1 | |a Hese, Soeren |e verfasserin |4 aut | |
| 700 | 1 | |a Hitchen, Esther |e verfasserin |4 aut | |
| 700 | 1 | |a Hoffmann, Per |e verfasserin |4 aut | |
| 700 | 1 | |a Jia, Tianye |e verfasserin |4 aut | |
| 700 | 1 | |a Jirsa, Viktor |e verfasserin |4 aut | |
| 700 | 1 | |a Marquand, Andre F |e verfasserin |4 aut | |
| 700 | 1 | |a Nees, Frauke |e verfasserin |4 aut | |
| 700 | 1 | |a Nöthen, Markus M |e verfasserin |4 aut | |
| 700 | 1 | |a Novarino, Gaia |e verfasserin |4 aut | |
| 700 | 1 | |a Polemiti, Elli |e verfasserin |4 aut | |
| 700 | 1 | |a Ralser, Markus |e verfasserin |4 aut | |
| 700 | 1 | |a Rapp, Michael |e verfasserin |4 aut | |
| 700 | 1 | |a Schepanski, Kerstin |e verfasserin |4 aut | |
| 700 | 1 | |a Schikowski, Tamara |e verfasserin |4 aut | |
| 700 | 1 | |a Slater, Mel |e verfasserin |4 aut | |
| 700 | 1 | |a Sommer, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Stahl, Bernd Carsten |e verfasserin |4 aut | |
| 700 | 1 | |a Thompson, Paul M |e verfasserin |4 aut | |
| 700 | 1 | |a Twardziok, Sven |e verfasserin |4 aut | |
| 700 | 1 | |a van der Meer, Dennis |e verfasserin |4 aut | |
| 700 | 1 | |a Walter, Henrik |e verfasserin |4 aut | |
| 700 | 1 | |a Westlye, Lars |e verfasserin |4 aut | |
| 700 | 0 | |a environMENTAL Consortium |e verfasserin |4 aut | |
| 700 | 1 | |a Heinz, Andreas |e investigator |4 oth | |
| 700 | 1 | |a Lett, Tristram |e investigator |4 oth | |
| 700 | 1 | |a Vaidya, Nilakshi |e investigator |4 oth | |
| 700 | 1 | |a Serin, Emin |e investigator |4 oth | |
| 700 | 1 | |a Neidhart, Maja |e investigator |4 oth | |
| 700 | 1 | |a Jentsch, Marcel |e investigator |4 oth | |
| 700 | 1 | |a Eils, Roland |e investigator |4 oth | |
| 700 | 1 | |a Taron, Ulrike-Helene |e investigator |4 oth | |
| 700 | 1 | |a Schütz, Tatjana |e investigator |4 oth | |
| 700 | 1 | |a Banks, James Richard |e investigator |4 oth | |
| 700 | 1 | |a Meyer-Lindenberg, Andreas |e investigator |4 oth | |
| 700 | 1 | |a Tost, Heike |e investigator |4 oth | |
| 700 | 1 | |a Holz, Nathalie |e investigator |4 oth | |
| 700 | 1 | |a Schwarz, Emanuel |e investigator |4 oth | |
| 700 | 1 | |a Stringaris, Argyris |e investigator |4 oth | |
| 700 | 1 | |a Christmann, Nina |e investigator |4 oth | |
| 700 | 1 | |a Jansone, Karina |e investigator |4 oth | |
| 700 | 1 | |a Siehl, Sebastian |e investigator |4 oth | |
| 700 | 1 | |a Ask, Helga |e investigator |4 oth | |
| 700 | 1 | |a Fernández-Cabello, Sara |e investigator |4 oth | |
| 700 | 1 | |a Kjelkenes, Rikka |e investigator |4 oth | |
| 700 | 1 | |a Tschorn, Mira |e investigator |4 oth | |
| 700 | 1 | |a Böttger, Sarah Jane |e investigator |4 oth | |
| 700 | 1 | |a Bernas, Antoine |e investigator |4 oth | |
| 700 | 1 | |a Marr, Lena |e investigator |4 oth | |
| 700 | 1 | |a Feixas Viapiana, Guillem |e investigator |4 oth | |
| 700 | 1 | |a Eiroa-Orosa, Francisco José |e investigator |4 oth | |
| 700 | 1 | |a Gallego, Jaime |e investigator |4 oth | |
| 700 | 1 | |a Pastor, Alvaro |e investigator |4 oth | |
| 700 | 1 | |a Forstner, Andreas J |e investigator |4 oth | |
| 700 | 1 | |a Claus, Isabelle |e investigator |4 oth | |
| 700 | 1 | |a Miller, Abigail |e investigator |4 oth | |
| 700 | 1 | |a Heilmann-Heimbach, Stefanie |e investigator |4 oth | |
| 700 | 1 | |a Boye, Mona |e investigator |4 oth | |
| 700 | 1 | |a Wilbertz, Johannes |e investigator |4 oth | |
| 700 | 1 | |a Schmitt, Karen |e investigator |4 oth | |
| 700 | 1 | |a Petkoski, Spase |e investigator |4 oth | |
| 700 | 1 | |a Pitel, Séverine |e investigator |4 oth | |
| 700 | 1 | |a Otten, Lisa |e investigator |4 oth | |
| 700 | 1 | |a Athanasiadis, Anastasios-Polykarpos |e investigator |4 oth | |
| 700 | 1 | |a Pearmund, Charlie |e investigator |4 oth | |
| 700 | 1 | |a Spanlang, Bernhard |e investigator |4 oth | |
| 700 | 1 | |a Alvarez, Elena |e investigator |4 oth | |
| 700 | 1 | |a Sanchez, Mavi |e investigator |4 oth | |
| 700 | 1 | |a Giner, Arantxa |e investigator |4 oth | |
| 700 | 1 | |a Renner, Paul |e investigator |4 oth | |
| 700 | 1 | |a Gong, Yanting |e investigator |4 oth | |
| 700 | 1 | |a Dai, Yuxiang |e investigator |4 oth | |
| 700 | 1 | |a Xia, Yunman |e investigator |4 oth | |
| 700 | 1 | |a Chang, Xiao |e investigator |4 oth | |
| 700 | 1 | |a Liu, Jingyu |e investigator |4 oth | |
| 700 | 1 | |a Young, Allan |e investigator |4 oth | |
| 700 | 1 | |a Ogoh, George |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t JAMA psychiatry |d 2013 |g 80(2023), 10 vom: 01. Okt., Seite 1066-1074 |w (DE-627)NLM22071942X |x 2168-6238 |7 nnns |
| 773 | 1 | 8 | |g volume:80 |g year:2023 |g number:10 |g day:01 |g month:10 |g pages:1066-1074 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1001/jamapsychiatry.2023.2996 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 80 |j 2023 |e 10 |b 01 |c 10 |h 1066-1074 | ||