Effect of Physical Exercise-Based Rehabilitation on Long COVID : A Systematic Review and Meta-analysis

Copyright © 2023 by the American College of Sports Medicine..

PURPOSE: The number of persons living with post-coronavirus disease 2019 (COVID-19) conditions or long COVID continues to rise worldwide; however, the etiology and the treatment of long COVID remain nebulous. Therefore, efficient, feasible, and cost-effective therapeutic strategies for a large population with long COVID remain warranted. Physical exercise-based rehabilitation is a promising strategy for long COVID, although its therapeutic effects remain to be determined. This systematic review and meta-analysis aimed to examine the effects of physical exercise-based rehabilitation on long COVID.

METHODS: The electronic databases Medline, Embase, Global Health (Ovid), CINAHL (EBSCO), Web of Science, WHO Global Research Database on COVID-19, LitCovid, and Google Scholar were searched from their inception to November 2022. The identified articles were independently screened by three reviewers, and a random-effects model was used to determine the mean differences in the meta-analysis.

RESULTS: Twenty-three studies involving 1579 individuals who had COVID-19 (752 women) were included. Physical exercise-based rehabilitation showed beneficial effects on long COVID-related symptoms characterized by dyspnea, fatigue, and depression, as well as on the 6-min walk test, forced expiratory volume in 1 s/forced vital capacity, and quality of life in people who had COVID-19.

CONCLUSIONS: Physical exercise-based rehabilitation is a potential therapeutic strategy against long COVID and can be applied as a routine clinical practice in people who have recovered from COVID-19. However, customized physical exercise-based rehabilitation programs and their effects on specific types of long COVID require future large-scale studies.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

2023

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:56

Enthalten in:

Medicine and science in sports and exercise - 56(2023), 1 vom: 01. Jan., Seite 143-154

Sprache:

Englisch

Beteiligte Personen:

Zheng, Chen [VerfasserIn]
Chen, Xiang-Ke [VerfasserIn]
Sit, Cindy Hui-Ping [VerfasserIn]
Liang, Xiao [VerfasserIn]
Li, Ming-Hui [VerfasserIn]
Ma, Alvin Chun-Hang [VerfasserIn]
Wong, Stephen Heung-Sang [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Meta-Analysis
Systematic Review

Anmerkungen:

Date Completed 16.12.2023

Date Revised 16.12.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1249/MSS.0000000000003280

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM36085298X