SARS-CoV-2 transmission patterns in educational settings during the Alpha wave in Reggio-Emilia, Italy
Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved..
Different monitoring and control policies have been implemented in schools to minimize the spread of SARS-CoV-2. Transmission in schools has been hard to quantify due to the large proportion of asymptomatic carriers in young individuals. We applied a Bayesian approach to reconstruct the transmission chains between 284 SARS-CoV-2 infections ascertained during 87 school outbreak investigations conducted between March and April 2021 in Italy. Under the policy of reactive quarantines, we found that 42.5% (95%CrI: 29.5-54.3%) of infections among school attendees were caused by school contacts. The mean number of secondary cases infected at school by a positive individual during in-person education was estimated to be 0.33 (95%CrI: 0.23-0.43), with marked heterogeneity across individuals. Specifically, we estimated that only 26.0% (95%CrI: 17.6-34.1%) of students and school personnel who tested positive during in-person education caused at least one secondary infection at school. Positive individuals who attended school for at least 6 days before being isolated or quarantined infected on average 0.49 (95%CrI: 0.14-0.83) secondary cases. Our findings provide quantitative insights on the contribution of school transmission to the spread of SARS-CoV-2 in young individuals. Identifying positive cases within 5 days after exposure to their infector could reduce onward transmission at school by at least 30%.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:44 |
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| Enthalten in: |
Epidemics - 44(2023) vom: 15. Sept., Seite 100712 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Molina Grané, Carla [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 08.09.2023 Date Revised 26.09.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.epidem.2023.100712 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM360666035 |
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| 520 | |a Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved. | ||
| 520 | |a Different monitoring and control policies have been implemented in schools to minimize the spread of SARS-CoV-2. Transmission in schools has been hard to quantify due to the large proportion of asymptomatic carriers in young individuals. We applied a Bayesian approach to reconstruct the transmission chains between 284 SARS-CoV-2 infections ascertained during 87 school outbreak investigations conducted between March and April 2021 in Italy. Under the policy of reactive quarantines, we found that 42.5% (95%CrI: 29.5-54.3%) of infections among school attendees were caused by school contacts. The mean number of secondary cases infected at school by a positive individual during in-person education was estimated to be 0.33 (95%CrI: 0.23-0.43), with marked heterogeneity across individuals. Specifically, we estimated that only 26.0% (95%CrI: 17.6-34.1%) of students and school personnel who tested positive during in-person education caused at least one secondary infection at school. Positive individuals who attended school for at least 6 days before being isolated or quarantined infected on average 0.49 (95%CrI: 0.14-0.83) secondary cases. Our findings provide quantitative insights on the contribution of school transmission to the spread of SARS-CoV-2 in young individuals. Identifying positive cases within 5 days after exposure to their infector could reduce onward transmission at school by at least 30% | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Mancuso, Pamela |e verfasserin |4 aut | |
| 700 | 1 | |a Vicentini, Massimo |e verfasserin |4 aut | |
| 700 | 1 | |a Venturelli, Francesco |e verfasserin |4 aut | |
| 700 | 1 | |a Djuric, Olivera |e verfasserin |4 aut | |
| 700 | 1 | |a Manica, Mattia |e verfasserin |4 aut | |
| 700 | 1 | |a Guzzetta, Giorgio |e verfasserin |4 aut | |
| 700 | 1 | |a Marziano, Valentina |e verfasserin |4 aut | |
| 700 | 1 | |a Zardini, Agnese |e verfasserin |4 aut | |
| 700 | 1 | |a d'Andrea, Valeria |e verfasserin |4 aut | |
| 700 | 1 | |a Trentini, Filippo |e verfasserin |4 aut | |
| 700 | 1 | |a Bisaccia, Eufemia |e verfasserin |4 aut | |
| 700 | 1 | |a Larosa, Elisabetta |e verfasserin |4 aut | |
| 700 | 1 | |a Cilloni, Silvia |e verfasserin |4 aut | |
| 700 | 1 | |a Cassinadri, Maria Teresa |e verfasserin |4 aut | |
| 700 | 1 | |a Pezzotti, Patrizio |e verfasserin |4 aut | |
| 700 | 1 | |a Ajelli, Marco |e verfasserin |4 aut | |
| 700 | 1 | |a Rossi, Paolo Giorgi |e verfasserin |4 aut | |
| 700 | 1 | |a Merler, Stefano |e verfasserin |4 aut | |
| 700 | 1 | |a Poletti, Piero |e verfasserin |4 aut | |
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