Evaluating the performance of large language models : ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders

© 2023 The Authors. Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology..

This study explores the utility of the large language models (LLMs), specifically ChatGPT and Google Bard, in predicting neuropathologic diagnoses from clinical summaries. A total of 25 cases of neurodegenerative disorders presented at Mayo Clinic brain bank Clinico-Pathological Conferences were analyzed. The LLMs provided multiple pathologic diagnoses and their rationales, which were compared with the final clinical diagnoses made by physicians. ChatGPT-3.5, ChatGPT-4, and Google Bard correctly made primary diagnoses in 32%, 52%, and 40% of cases, respectively, while correct diagnoses were included in 76%, 84%, and 76% of cases, respectively. These findings highlight the potential of artificial intelligence tools like ChatGPT in neuropathology, suggesting they may facilitate more comprehensive discussions in clinicopathological conferences.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:34

Enthalten in:

Brain pathology (Zurich, Switzerland) - 34(2024), 3 vom: 08. Apr., Seite e13207

Sprache:

Englisch

Beteiligte Personen:

Koga, Shunsuke [VerfasserIn]
Martin, Nicholas B [VerfasserIn]
Dickson, Dennis W [VerfasserIn]

Links:

Volltext

Themen:

Artificial intelligence
CPC
ChatGPT
Clinicopathological conference
Google Bard
Large language model
Letter
Neuropathology
Pathology

Anmerkungen:

Date Completed 12.04.2024

Date Revised 25.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/bpa.13207

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM360528392