Aseptic meningitis followed by mononeuritis multiplex in a patient with primary Sjögren's syndrome
A 38-year-old woman was admitted to hospital because of fever and headache. Increased cerebrospinal cell count and protein without evidence of infection led to a diagnosis of aseptic meningitis. Although she improved with acyclovir and glyceol, she experienced left forearm pain and sensory disturbance with drop fingers. Poor derivation of compound muscle action potentials in the left radial nerve was observed, leading to a diagnosis of mononeuritis multiplex with sensorimotor neuropathy. Because the patient had primary Sjögren's syndrome with anti-Ro/SS-A antibody and salivary gland hypofunction, treatment with methylprednisolone, intravenous immunoglobulin, and intravenous cyclophosphamide was followed by oral glucocorticoid therapy. After these intensive therapies, her drop fingers gradually improved, although sensory disturbance remained. In conclusion, we report a case of aseptic meningitis and subsequent mononeuritis multiplex that was successfully treated with intensive immunotherapy in a patient with primary Sjögren's syndrome.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:51 |
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| Enthalten in: |
The Journal of international medical research - 51(2023), 8 vom: 16. Aug., Seite 3000605231189121 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Nakamura, Hideki [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-Ro/SS-A antibody |
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| Anmerkungen: |
Date Completed 08.08.2023 Date Revised 10.08.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.1177/03000605231189121 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM360480519 |
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| 245 | 1 | 0 | |a Aseptic meningitis followed by mononeuritis multiplex in a patient with primary Sjögren's syndrome |
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| 520 | |a A 38-year-old woman was admitted to hospital because of fever and headache. Increased cerebrospinal cell count and protein without evidence of infection led to a diagnosis of aseptic meningitis. Although she improved with acyclovir and glyceol, she experienced left forearm pain and sensory disturbance with drop fingers. Poor derivation of compound muscle action potentials in the left radial nerve was observed, leading to a diagnosis of mononeuritis multiplex with sensorimotor neuropathy. Because the patient had primary Sjögren's syndrome with anti-Ro/SS-A antibody and salivary gland hypofunction, treatment with methylprednisolone, intravenous immunoglobulin, and intravenous cyclophosphamide was followed by oral glucocorticoid therapy. After these intensive therapies, her drop fingers gradually improved, although sensory disturbance remained. In conclusion, we report a case of aseptic meningitis and subsequent mononeuritis multiplex that was successfully treated with intensive immunotherapy in a patient with primary Sjögren's syndrome | ||
| 650 | 4 | |a Case Reports | |
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| 650 | 4 | |a Aseptic meningitis | |
| 650 | 4 | |a Sjögren’s syndrome | |
| 650 | 4 | |a anti-Ro/SS-A antibody | |
| 650 | 4 | |a drop finger | |
| 650 | 4 | |a immunotherapy | |
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| 700 | 1 | |a Tanikawa, Yutaka |e verfasserin |4 aut | |
| 700 | 1 | |a Nishihara, Masahiro |e verfasserin |4 aut | |
| 700 | 1 | |a Tsukamoto, Masako |e verfasserin |4 aut | |
| 700 | 1 | |a Nagasawa, Yosuke |e verfasserin |4 aut | |
| 700 | 1 | |a Akiya, Kumiko |e verfasserin |4 aut | |
| 700 | 1 | |a Natori, Naotoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Kitamura, Noboru |e verfasserin |4 aut | |
| 700 | 1 | |a Takayama, Tadateru |e verfasserin |4 aut | |
| 700 | 1 | |a Nakajima, Hideto |e verfasserin |4 aut | |
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