Clinical standards for drug-susceptible TB in children and adolescents

BACKGROUND: These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.METHODS: Fifty-two global experts in paediatric TB participated in a Delphi consensus process. After eight rounds of revisions, 51/52 (98%) participants endorsed the final document.RESULTS: Eight standards were identified: Standard 1, Age and developmental stage are critical considerations in the assessment and management of TB; Standard 2, Children and adolescents with symptoms and signs of TB disease should undergo prompt evaluation, and diagnosis and treatment initiation should not depend on microbiological confirmation; Standard 3, Treatment initiation is particularly urgent in children and adolescents with presumptive TB meningitis and disseminated (miliary) TB; Standard 4, Children and adolescents should be treated with an appropriate weight-based regimen; Standard 5, Treating TB infection (TBI) is important to prevent disease; Standard 6, Children and adolescents should receive home-based/community-based treatment support whenever possible; Standard 7, Children, adolescents, and their families should be provided age-appropriate support to optimise engagement in care and clinical outcomes; and Standard 8, Case reporting and contact tracing should be conducted for each child and adolescent.CONCLUSION: These consensus-based clinical standards, which should be adapted to local contexts, will improve the care of children and adolescents affected by TB.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 27(2023), 8 vom: 01. Aug., Seite 584-598

Sprache:

Englisch

Beteiligte Personen:

Chiang, S S [VerfasserIn]
Graham, S M [VerfasserIn]
Schaaf, H S [VerfasserIn]
Marais, B J [VerfasserIn]
Sant'Anna, C C [VerfasserIn]
Sharma, S [VerfasserIn]
Starke, J R [VerfasserIn]
Triasih, R [VerfasserIn]
Achar, J [VerfasserIn]
Amanullah, F [VerfasserIn]
Armitage, L Y [VerfasserIn]
Aurilio, R B [VerfasserIn]
Buck, W C [VerfasserIn]
Centis, R [VerfasserIn]
Chabala, C [VerfasserIn]
Cruz, A T [VerfasserIn]
Demers, A-M [VerfasserIn]
du Preez, K [VerfasserIn]
Enimil, A [VerfasserIn]
Furin, J [VerfasserIn]
Garcia-Prats, A J [VerfasserIn]
Gonzalez, N E [VerfasserIn]
Hoddinott, G [VerfasserIn]
Isaakidis, P [VerfasserIn]
Jaganath, D [VerfasserIn]
Kabra, S K [VerfasserIn]
Kampmann, B [VerfasserIn]
Kay, A [VerfasserIn]
Kitai, I [VerfasserIn]
Lopez-Varela, E [VerfasserIn]
Maleche-Obimbo, E [VerfasserIn]
Malaspina, F Mestanza [VerfasserIn]
Velásquez, J Niederbacher [VerfasserIn]
Nuttall, J J C [VerfasserIn]
Oliwa, J N [VerfasserIn]
Andrade, I Orozco [VerfasserIn]
Perez-Velez, C M [VerfasserIn]
Rabie, H [VerfasserIn]
Seddon, J A [VerfasserIn]
Sekadde, M P [VerfasserIn]
Shen, A [VerfasserIn]
Skrahina, A [VerfasserIn]
Soriano-Arandes, A [VerfasserIn]
Steenhoff, A P [VerfasserIn]
Tebruegge, M [VerfasserIn]
Tovar, M A [VerfasserIn]
Tsogt, B [VerfasserIn]
van der Zalm, M M [VerfasserIn]
Welch, H [VerfasserIn]
Migliori, G B [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 01.08.2023

Date Revised 07.11.2023

published: Print

Citation Status MEDLINE

doi:

10.5588/ijtld.23.0085

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM359919189