Update on the diagnosis of tuberculosis

Copyright © 2023 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved..

BACKGROUND: Tuberculosis (TB) remains a global public health threat, and the development of rapid and precise diagnostic tools is the key to enabling the early start of treatment, monitoring response to treatment, and preventing the spread of the disease.

OBJECTIVES: An overview of recent progress in host- and pathogen-based TB diagnostics.

SOURCES: We conducted a PubMed search of recent relevant articles and guidelines on TB screening and diagnosis.

CONTENT: An overview of currently used methods and perspectives in the following areas of TB diagnostics is provided: immune-based diagnostics, X-ray, clinical symptoms and scores, cough detection, culture of Mycobacterium tuberculosis and identifying its resistance profile using phenotypic and genotypic methods, including next-generation sequencing, sputum- and non-sputum-based molecular diagnosis of TB and monitoring of response to treatment.

IMPLICATIONS: A brief overview of the most relevant advances and changes in international guidelines regarding screening and diagnosing TB is provided in this review. It aims at reviewing all relevant areas of diagnostics, including both pathogen- and host-based methods.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - year:2023

Enthalten in:

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - (2023) vom: 23. Juli

Sprache:

Englisch

Beteiligte Personen:

Kontsevaya, Irina [VerfasserIn]
Cabibbe, Andrea Maurizio [VerfasserIn]
Cirillo, Daniela Maria [VerfasserIn]
DiNardo, Andrew R [VerfasserIn]
Frahm, Nicole [VerfasserIn]
Gillespie, Stephen H [VerfasserIn]
Holtzman, David [VerfasserIn]
Meiwes, Lennard [VerfasserIn]
Petruccioli, Elisa [VerfasserIn]
Reimann, Maja [VerfasserIn]
Ruhwald, Morten [VerfasserIn]
Sabiiti, Wilber [VerfasserIn]
Saluzzo, Francesca [VerfasserIn]
Tagliani, Elisa [VerfasserIn]
Goletti, Delia [VerfasserIn]

Links:

Volltext

Themen:

Diagnostics
Infectious disease
Journal Article
Non-sputum based
Novel diagnostics
Review

Anmerkungen:

Date Revised 13.08.2023

published: Print-Electronic

Citation Status Publisher

doi:

10.1016/j.cmi.2023.07.014

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM359911374