Biochemical responses of the mussel Perna perna after exposure to environmental concentrations of the UV filter Benzophenone-3
Personal care products, such as UV filters, are frequently present in aquatic ecosystems, but studies on their impact on marine organisms are still scarce. Here we addressed the effects of benzophenone-3 (BP-3) on the antioxidant status of Perna perna mussels exposed to concentrations of 0.1 and 3 μg.L-1 for 72 h and 7 days. Glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), glucose-6-phosphate dehydrogenase (G6PDH) activity and lipoperoxidation (MDA) were evaluated in the gills. A significant reduction (p < 0.05) in the activity of G6PDH and GPx was observed after exposure for 7 days to 0.1 µg.L-1. However, no significant differences were observed in GST activity and MDA levels, independently of the exposure time. Principal component analysis (PCA) showed an association of BP-3 highest concentration with GR and MDA at 72 h and only with GR at 7 days of exposure. Similarly, the integrated biomarker response (IBR) demonstrated GR and MDA alterations. In conclusion, environmentally relevant concentrations of BP-3 altered antioxidant and auxiliary enzymes, which could cause long-term damage to P.perna mussels. The need to implement more efficient techniques in wastewater treatment systems is pointed out, especially in summer, when UV filters are used more frequently and abundantly.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:53 |
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| Enthalten in: |
Xenobiotica; the fate of foreign compounds in biological systems - 53(2023), 4 vom: 21. Apr., Seite 309-319 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cruz, Gabriel S [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 03.08.2023 Date Revised 03.08.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1080/00498254.2023.2233022 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM359773753 |
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| 100 | 1 | |a Cruz, Gabriel S |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Biochemical responses of the mussel Perna perna after exposure to environmental concentrations of the UV filter Benzophenone-3 |
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| 500 | |a Date Revised 03.08.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Personal care products, such as UV filters, are frequently present in aquatic ecosystems, but studies on their impact on marine organisms are still scarce. Here we addressed the effects of benzophenone-3 (BP-3) on the antioxidant status of Perna perna mussels exposed to concentrations of 0.1 and 3 μg.L-1 for 72 h and 7 days. Glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), glucose-6-phosphate dehydrogenase (G6PDH) activity and lipoperoxidation (MDA) were evaluated in the gills. A significant reduction (p < 0.05) in the activity of G6PDH and GPx was observed after exposure for 7 days to 0.1 µg.L-1. However, no significant differences were observed in GST activity and MDA levels, independently of the exposure time. Principal component analysis (PCA) showed an association of BP-3 highest concentration with GR and MDA at 72 h and only with GR at 7 days of exposure. Similarly, the integrated biomarker response (IBR) demonstrated GR and MDA alterations. In conclusion, environmentally relevant concentrations of BP-3 altered antioxidant and auxiliary enzymes, which could cause long-term damage to P.perna mussels. The need to implement more efficient techniques in wastewater treatment systems is pointed out, especially in summer, when UV filters are used more frequently and abundantly | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Oxybenzone | |
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| 700 | 1 | |a Saldaña-Serrano, Miguel |e verfasserin |4 aut | |
| 700 | 1 | |a Bastolla, Camila L V |e verfasserin |4 aut | |
| 700 | 1 | |a Lima, Daína |e verfasserin |4 aut | |
| 700 | 1 | |a Gomes, Carlos H A M |e verfasserin |4 aut | |
| 700 | 1 | |a de Castro, Micheli R |e verfasserin |4 aut | |
| 700 | 1 | |a Dos Santos, Uclédia R A |e verfasserin |4 aut | |
| 700 | 1 | |a Coutinho, Gabriel S |e verfasserin |4 aut | |
| 700 | 1 | |a Mattos, Jacó J |e verfasserin |4 aut | |
| 700 | 1 | |a Marques, Maria R F |e verfasserin |4 aut | |
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