Research progress on the preparation and application of flavonoid nanocrystals
Flavonoids have been reported to possess significant pharmacological activities,such as antioxidant, anti-inflammatory and anticancer effects. However, the low solubility and low bioavailability limits their clinical application. Nanocrystal technology can solve the delivery problems of flavonoids by reducing particle size, increasing the solubility of insoluble drugs and improving their bioavailability. This article summaries nanosuspension preparation methods and the stabilizers for flavonoid nanocrystals, and reviews the drug delivery routes including oral, Injection and transdermal of flavonoid nanocrystals, to provide information for further research on nanocrystal delivery system of flavonoids.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:52 |
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| Enthalten in: |
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 52(2023), 3 vom: 25. Juni, Seite 338-348 |
| Sprache: |
Englisch |
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| Weiterer Titel: |
黄酮类化合物纳米晶体的制备及应用研究进展 |
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| Beteiligte Personen: |
Tian, Yiting [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-Inflammatory Agents |
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| Anmerkungen: |
Date Completed 24.07.2023 Date Revised 28.11.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.3724/zdxbyxb-2023-0180 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM359773575 |
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| 245 | 1 | 0 | |a Research progress on the preparation and application of flavonoid nanocrystals |
| 246 | 3 | 3 | |a 黄酮类化合物纳米晶体的制备及应用研究进展 |
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| 520 | |a Flavonoids have been reported to possess significant pharmacological activities,such as antioxidant, anti-inflammatory and anticancer effects. However, the low solubility and low bioavailability limits their clinical application. Nanocrystal technology can solve the delivery problems of flavonoids by reducing particle size, increasing the solubility of insoluble drugs and improving their bioavailability. This article summaries nanosuspension preparation methods and the stabilizers for flavonoid nanocrystals, and reviews the drug delivery routes including oral, Injection and transdermal of flavonoid nanocrystals, to provide information for further research on nanocrystal delivery system of flavonoids | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Drug delivery | |
| 650 | 4 | |a Flavonoids | |
| 650 | 4 | |a Nanocrystal | |
| 650 | 4 | |a Nanosuspension | |
| 650 | 4 | |a Preparation method | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Stabilizer | |
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| 650 | 7 | |a Anti-Inflammatory Agents |2 NLM | |
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| 700 | 1 | |a Ma, Huiping |e verfasserin |4 aut | |
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