Respiratory syncytial virus infection : survival experience in a cohort of children inpatients
Copyright © 2023 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved..
OBJECTIVE: The objective of this study was to assess the survival experience of children hospitalized with laboratory-confirmed respiratory syncytial virus (RSV) infection due to bronchiolitis.
STUDY DESIGN: This was a nationwide retrospective cohort study conducted in Mexico.
METHODS: We analyzed data from 436 children aged 5 years and younger, with symptom onset between August 2021 and November 2022. The Kaplan-Meier method was used to compute survivor functions and their 95% confidence intervals (CI).
RESULTS: High survival rates were observed, particularly within the first three weeks of hospital admission. The 3-day survival rate was 99.8% (CI 98.4-99.9%), which decreased to 98.9% (CI 96.5-99.7%), 97.5% (CI 91.9-99.3%), 86.7% (CI 48.2-97.2%), and 69.4% (CI 24.2-91.0%) on days 7, 14, 21, and 28 of hospital stay, respectively. We documented a total of 5 fatal outcomes, resulting in a mortality rate of 2.1 (95% CI 0.9-5.1) per 1,000 person-days.
CONCLUSIONS: Our study analyzed a large cohort of pediatric patients with bronchiolitis caused by RSV infection, providing valuable insights into the in-hospital progression of this disease.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:221 |
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| Enthalten in: |
Public health - 221(2023) vom: 05. Aug., Seite 181-183 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Murillo-Zamora, E [VerfasserIn] |
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| Links: |
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| Themen: |
Bronchiolitis |
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| Anmerkungen: |
Date Completed 08.08.2023 Date Revised 08.08.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.puhe.2023.06.020 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM359740863 |
|---|
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved. | ||
| 520 | |a OBJECTIVE: The objective of this study was to assess the survival experience of children hospitalized with laboratory-confirmed respiratory syncytial virus (RSV) infection due to bronchiolitis | ||
| 520 | |a STUDY DESIGN: This was a nationwide retrospective cohort study conducted in Mexico | ||
| 520 | |a METHODS: We analyzed data from 436 children aged 5 years and younger, with symptom onset between August 2021 and November 2022. The Kaplan-Meier method was used to compute survivor functions and their 95% confidence intervals (CI) | ||
| 520 | |a RESULTS: High survival rates were observed, particularly within the first three weeks of hospital admission. The 3-day survival rate was 99.8% (CI 98.4-99.9%), which decreased to 98.9% (CI 96.5-99.7%), 97.5% (CI 91.9-99.3%), 86.7% (CI 48.2-97.2%), and 69.4% (CI 24.2-91.0%) on days 7, 14, 21, and 28 of hospital stay, respectively. We documented a total of 5 fatal outcomes, resulting in a mortality rate of 2.1 (95% CI 0.9-5.1) per 1,000 person-days | ||
| 520 | |a CONCLUSIONS: Our study analyzed a large cohort of pediatric patients with bronchiolitis caused by RSV infection, providing valuable insights into the in-hospital progression of this disease | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Bronchiolitis | |
| 650 | 4 | |a Child | |
| 650 | 4 | |a Respiratory syncytial virus infections | |
| 650 | 4 | |a Survival | |
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| 700 | 1 | |a Bricio-Barrios, J A |e verfasserin |4 aut | |
| 700 | 1 | |a Ríos-Bracamontes, E F |e verfasserin |4 aut | |
| 700 | 1 | |a Trujillo, X |e verfasserin |4 aut | |
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