Lessons learned from U.S. rapid antiretroviral therapy initiation programs

BACKGROUND: Rapid antiretroviral therapy initiation (R-ART) for treatment of HIV has been recommended since 2017, however it has not been adopted widely across the US.

PURPOSE: The study purpose was to understand facilitators and barriers to R-ART implementation in the U.S.

RESEARCH DESIGN: This was a qualitative design involving semi-structured interviews.

STUDY SAMPLE: The study sample was comprised of the medical leadership of nine US HIV clinics that were early implementers of R-ART.

DATA COLLECTION AND ANALYSIS: In-depth, semi-structured interviews were performed. The Consolidated Framework for Implementation Research (CFIR) was used to guide thematic analysis.

RESULTS: We identified three main content areas: strong scientific rationale for R-ART, buy-in from multiple key stakeholders, and the condensed timeline of R-ART. The CFIR construct of Evidence Strength and Quality was cited as an important factor in R-ART implementation. Buy-in from key stakeholders and immediate access to medications ensured the success of R-ART implementation. Patient acceptance of the condensed timeline for ART initiation was facilitated when presented in a patient-centered manner, including empathetic communication and addressing other patient needs concurrently. The condensed timeline of R-ART presented logistical challenges and opportunities for the development of intense patient-provider relationships.

CONCLUSIONS: Results from the analysis showed that R-ART implementation should address the following: 1) logistical planning to implement HIV treatment with a condensed timeline 2) patients' mixed reactions to a new HIV diagnosis and 3) the high cost of HIV medications.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:34

Enthalten in:

International journal of STD & AIDS - 34(2023), 13 vom: 12. Nov., Seite 945-955

Sprache:

Englisch

Beteiligte Personen:

Doshi, Rupali K [VerfasserIn]
Hull, Shawnika [VerfasserIn]
Broun, Aaron [VerfasserIn]
Boyani, Saanjh [VerfasserIn]
Moch, Darryl [VerfasserIn]
Visconti, Adam J [VerfasserIn]
Castel, Amanda D [VerfasserIn]
Baral, Stefan [VerfasserIn]
Colasanti, Jonathan [VerfasserIn]
Rodriguez, Allan E [VerfasserIn]
Jones, Joyce [VerfasserIn]
Coffey, Susa [VerfasserIn]
Monroe, Anne K [VerfasserIn]

Links:

Volltext

Themen:

CFIR
HIV/AIDS
Implementation
Journal Article
Qualitative
Research Support, N.I.H., Extramural
Treatment initiation

Anmerkungen:

Date Completed 31.10.2023

Date Revised 09.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/09564624231185622

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM359618812