Dual-layers Raman reporter-tagged AuAg combined with core-satellite assemblies for SERS detection of Zearalenone
Copyright © 2023 Elsevier Ltd. All rights reserved..
Zearalenone (ZEN) is a prevalent mycotoxin identified in corn. A SERS-based immunosensor by constructing core-satellite assemblies was developed for ZEN detection. ZEN monoclonal antibody modified gold nanostars (AuNSs) were fabricated as the capture probe (core). The Raman signal probes (satellites) utilized ZEN antigen linked to the core-shell structures loaded with two layers of Raman reporter molecules (AuMBAAgMBANPs). The coupling between AuNSs and AuMBA@AgMBANPs can produce a poweful electromagnetic field, thus considerably amplifying the Raman signal. The detection range of ZEN for corn samples under the optimal conditions was 5 ∼ 400 μg/kg with a LOD of 3 μg/kg, which completely satisfying the requirement of maximum residual level (60 μg/kg). Moreover, the proposed SERS method was consistent with the HPLC-FLD method for the detection of ZEN in naturally contaminated corn samples (90.58% ∼ 105.29%). Conclusively, fabricated immunosensor with exceptional sensitivity and specificity broaden the application of SERS in mycotoxin detection.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:429 |
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| Enthalten in: |
Food chemistry - 429(2023) vom: 15. Dez., Seite 136834 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yin, Limei [VerfasserIn] |
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| Links: |
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| Themen: |
3M4G523W1G |
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| Anmerkungen: |
Date Completed 24.08.2023 Date Revised 24.08.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.foodchem.2023.136834 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM359540368 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier Ltd. All rights reserved. | ||
| 520 | |a Zearalenone (ZEN) is a prevalent mycotoxin identified in corn. A SERS-based immunosensor by constructing core-satellite assemblies was developed for ZEN detection. ZEN monoclonal antibody modified gold nanostars (AuNSs) were fabricated as the capture probe (core). The Raman signal probes (satellites) utilized ZEN antigen linked to the core-shell structures loaded with two layers of Raman reporter molecules (AuMBAAgMBANPs). The coupling between AuNSs and AuMBA@AgMBANPs can produce a poweful electromagnetic field, thus considerably amplifying the Raman signal. The detection range of ZEN for corn samples under the optimal conditions was 5 ∼ 400 μg/kg with a LOD of 3 μg/kg, which completely satisfying the requirement of maximum residual level (60 μg/kg). Moreover, the proposed SERS method was consistent with the HPLC-FLD method for the detection of ZEN in naturally contaminated corn samples (90.58% ∼ 105.29%). Conclusively, fabricated immunosensor with exceptional sensitivity and specificity broaden the application of SERS in mycotoxin detection | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Core-satellite assemblies | |
| 650 | 4 | |a Core-shell nanostructure | |
| 650 | 4 | |a Immunosensor | |
| 650 | 4 | |a Surface-enhanced Raman scattering (SERS) | |
| 650 | 4 | |a Zearalenone | |
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| 700 | 1 | |a You, Tianyan |e verfasserin |4 aut | |
| 700 | 1 | |a Arslan, Muhammad |e verfasserin |4 aut | |
| 700 | 1 | |a El-Seedi, Hesham R |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Zhiming |e verfasserin |4 aut | |
| 700 | 1 | |a Zou, Xiaobo |e verfasserin |4 aut | |
| 700 | 1 | |a Cai, Jianrong |e verfasserin |4 aut | |
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