A smartphone digital image colorimetric method based on nanoparticles for determination of lamotrigine
Aim: A colorimetric approach for quantification of lamotrigine using spectrophotometric and smartphone image analysis is described in this study. Methods: For full optimization and validation procedures, UV-visible spectroscopy was used, and image analysis was carried out with the help of an app (PhotoMetrix PRO®). Then, as a multivariate calibration method, parallel factor analysis was used for data analysis. Results: The results demonstrated the capacity of these methods to estimate lamotrigine concentrations in the range of 0.1-7.0 μg.ml-1 in exhaled breath condensate, indicating the value of using digital images and smartphone applications in combination with chemometric tools. Conclusion: The image analysis can be superior for its fast and reliable lamotrigine analysis in biological samples.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
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| Enthalten in: |
Bioanalysis - 15(2023), 15 vom: 11. Aug., Seite 915-926 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sefid-Sefidehkhan, Yasaman [VerfasserIn] |
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| Links: |
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| Themen: |
Anticonvulsants |
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| Anmerkungen: |
Date Completed 07.09.2023 Date Revised 07.09.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.4155/bio-2023-0075 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM359328121 |
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| 245 | 1 | 2 | |a A smartphone digital image colorimetric method based on nanoparticles for determination of lamotrigine |
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| 500 | |a Date Revised 07.09.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Aim: A colorimetric approach for quantification of lamotrigine using spectrophotometric and smartphone image analysis is described in this study. Methods: For full optimization and validation procedures, UV-visible spectroscopy was used, and image analysis was carried out with the help of an app (PhotoMetrix PRO®). Then, as a multivariate calibration method, parallel factor analysis was used for data analysis. Results: The results demonstrated the capacity of these methods to estimate lamotrigine concentrations in the range of 0.1-7.0 μg.ml-1 in exhaled breath condensate, indicating the value of using digital images and smartphone applications in combination with chemometric tools. Conclusion: The image analysis can be superior for its fast and reliable lamotrigine analysis in biological samples | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Mokhtari, Mehdi |e verfasserin |4 aut | |
| 700 | 1 | |a Jouyban, Abolghasem |e verfasserin |4 aut | |
| 700 | 1 | |a Khoshkam, Maryam |e verfasserin |4 aut | |
| 700 | 1 | |a Khoubnasabjafari, Maryam |e verfasserin |4 aut | |
| 700 | 1 | |a Jouyban-Gharamaleki, Vahid |e verfasserin |4 aut | |
| 700 | 1 | |a Rahimpour, Elaheh |e verfasserin |4 aut | |
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