New Perspectives in Post-Surgical Acute Kidney Injury During Sepsis
Copyright by Società Italiana di Nefrologia SIN, Rome,Italy..
Postoperative acute kidney injury (PO-AKI) is a common complication of major surgery that is strongly associated with short-term surgical complications and long-term adverse outcomes. Risk factors for PO-AKI include older age and comorbid diseases such as chronic kidney disease and diabetes mellitus. Sepsis is a common complication in patients undergoing surgery and is a major risk factor for the development of acute kidney injury (SA-AKI). Prevention of AKI in surgery patients is largely based on identification of high baseline risk, monitoring, and reduction of nephrotoxic insults. Early identification of patients at risk of AKI, or at risk of progressing to severe and/or persistent AKI, is crucial to the timely initiation of adequate supportive measures, including limiting further insults to the kidney. Although specific therapeutic options are limited, several clinical trials have evaluated the use of care bundles and extracorporeal techniques as potential therapeutic approaches.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
|---|---|
| Enthalten in: |
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia - 40(2023), 3 vom: 29. Juni |
| Sprache: |
Italienisch |
|---|
| Beteiligte Personen: |
Zambianchi, Loretta [VerfasserIn] |
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| Themen: |
AKI |
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| Anmerkungen: |
Date Completed 12.07.2023 Date Revised 18.07.2023 published: Electronic Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM359289452 |
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| 520 | |a Postoperative acute kidney injury (PO-AKI) is a common complication of major surgery that is strongly associated with short-term surgical complications and long-term adverse outcomes. Risk factors for PO-AKI include older age and comorbid diseases such as chronic kidney disease and diabetes mellitus. Sepsis is a common complication in patients undergoing surgery and is a major risk factor for the development of acute kidney injury (SA-AKI). Prevention of AKI in surgery patients is largely based on identification of high baseline risk, monitoring, and reduction of nephrotoxic insults. Early identification of patients at risk of AKI, or at risk of progressing to severe and/or persistent AKI, is crucial to the timely initiation of adequate supportive measures, including limiting further insults to the kidney. Although specific therapeutic options are limited, several clinical trials have evaluated the use of care bundles and extracorporeal techniques as potential therapeutic approaches | ||
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| 650 | 4 | |a biomarkers | |
| 650 | 4 | |a extracorporeal treatment | |
| 650 | 4 | |a sepsis | |
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| 700 | 1 | |a Cignesi, Denise |e verfasserin |4 aut | |
| 700 | 1 | |a Cristino, Stefania |e verfasserin |4 aut | |
| 700 | 1 | |a Angelini, Maria Laura |e verfasserin |4 aut | |
| 700 | 1 | |a Spazzoli, Alessandra |e verfasserin |4 aut | |
| 700 | 1 | |a Americo, Claudio |e verfasserin |4 aut | |
| 700 | 1 | |a Lifrieri, Maria Francesca |e verfasserin |4 aut | |
| 700 | 1 | |a Buscaroli, Andrea |e verfasserin |4 aut | |
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