Delirium, confusion, or altered mental status as a risk for abnormal head CT in older adults in the emergency department : A systematic review and meta-analysis
Copyright © 2023 Elsevier Inc. All rights reserved..
BACKGROUND: Altered mental status (including delirium) is a common presentations among older adults to the emergency department (ED). We aimed to report the association between altered mental status in older ED patients and acute abnormal findings on head computed tomogram (CT).
METHODS: A systematic review was conducted using Ovid Medline, Embase, Clinicaltrials.gov, Web of Science, and Cochrane Central from conception to April 8th, 2021. We included citations if they described patients aged 65 years or older who received head imaging at the time of ED assessment, and reported whether patients had delirium, confusion, or altered mental status. Screening, data extraction, and bias assessment were performed in duplicate. We estimated the odds ratios (OR) for abnormal neuroimaging in patients with altered mental status.
RESULTS: The search strategy identified 3031 unique citations, of which two studies reporting on 909 patients with delirium, confusion or altered mental status were included. No identified study formally assessed for delirium. The OR for abnormal head CT findings in patients with delirium, confusion or altered mental status was 0.35 (95% CI 0.031 to 3.97) compared to patients without delirium, confusion or altered mental status.
CONCLUSION: We did not find a statistically significant association between delirium, confusion or altered mental status and abnormal head CT findings in older ED patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:71 |
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| Enthalten in: |
The American journal of emergency medicine - 71(2023) vom: 15. Sept., Seite 190-194 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Lee, Sangil [VerfasserIn] |
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| Links: |
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| Themen: |
Altered mental status |
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| Anmerkungen: |
Date Completed 07.08.2023 Date Revised 07.08.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ajem.2023.06.034 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM359240763 |
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| 500 | |a Date Revised 07.08.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: Altered mental status (including delirium) is a common presentations among older adults to the emergency department (ED). We aimed to report the association between altered mental status in older ED patients and acute abnormal findings on head computed tomogram (CT) | ||
| 520 | |a METHODS: A systematic review was conducted using Ovid Medline, Embase, Clinicaltrials.gov, Web of Science, and Cochrane Central from conception to April 8th, 2021. We included citations if they described patients aged 65 years or older who received head imaging at the time of ED assessment, and reported whether patients had delirium, confusion, or altered mental status. Screening, data extraction, and bias assessment were performed in duplicate. We estimated the odds ratios (OR) for abnormal neuroimaging in patients with altered mental status | ||
| 520 | |a RESULTS: The search strategy identified 3031 unique citations, of which two studies reporting on 909 patients with delirium, confusion or altered mental status were included. No identified study formally assessed for delirium. The OR for abnormal head CT findings in patients with delirium, confusion or altered mental status was 0.35 (95% CI 0.031 to 3.97) compared to patients without delirium, confusion or altered mental status | ||
| 520 | |a CONCLUSION: We did not find a statistically significant association between delirium, confusion or altered mental status and abnormal head CT findings in older ED patients | ||
| 650 | 4 | |a Meta-Analysis | |
| 650 | 4 | |a Systematic Review | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Altered mental status | |
| 650 | 4 | |a Delirium | |
| 650 | 4 | |a Head CT | |
| 700 | 1 | |a Cavalier, Faithe R |e verfasserin |4 aut | |
| 700 | 1 | |a Hayes, Jane M |e verfasserin |4 aut | |
| 700 | 1 | |a Doering, Michelle |e verfasserin |4 aut | |
| 700 | 1 | |a Lo, Alexander X |e verfasserin |4 aut | |
| 700 | 1 | |a Khoujah, Danya |e verfasserin |4 aut | |
| 700 | 1 | |a Howard, Matthew A |e verfasserin |4 aut | |
| 700 | 1 | |a de Wit, Kerstin |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Shan W |e verfasserin |4 aut | |
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