Trans-nasal sphenopalatine ganglion block for post-dural puncture headache management : a meta-analysis of randomized trials

Copyright © 2023 Sociedade Brasileira de Anestesiologia. Published by Elsevier España S.L.U. All rights reserved..

OBJECTIVE: To evaluate the efficacy and safety of trans-nasal Sphenopalatine Ganglion (SPG) block over other treatments for Post-Dural Puncture Headache (PDPH) management.

METHODS: A systematic literature search was conducted on databases for Randomized Controlled Trials (RCTs) comparing trans-nasal SPG blockade for the management of PDPH over other treatment modalities. All outcomes were pooled using the Mantel-Haenszel method and random effect model. Analyses of all outcomes were performed as a subgroup based on the type of control interventions (conservative, intranasal lignocaine puffs, sham, and Greater Occipital Nerve [GON] block). The quality of evidence was assessed using the GRADE approach.

RESULTS: After screening 1748 relevant articles, 9 RCTs comparing SPG block with other interventions (6 conservative treatments, 1 sham, 1 GON and 1 intranasal lidocaine puff) were included in this meta-analysis. SPG block demonstrated superiority over conservative treatment in pain reduction at 30 min, 1 h, 2 h, 4 h after interventions and treatment failures with "very low" to "moderate" quality of evidence. The SPG block failed to demonstrate superiority over conservative treatment in pain reduction beyond 6 h, need for rescue treatment, and adverse events. SPG block demonstrated superiority over intranasal lignocaine puff in pain reduction at 30 min, 1 h, 6 h, and 24 h after interventions. SPG block did not show superiority or equivalence in all efficacy and safety outcomes as compared to sham and GON block.

CONCLUSION: Very Low to moderate quality evidence suggests the superiority of SPG block over conservative treatment and lignocaine puff for short-term pain relief from PDPH.

PROSPERO REGISTRATION: CRD42021291707.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:73

Enthalten in:

Brazilian journal of anesthesiology (Elsevier) - 73(2023), 6 vom: 06. Nov., Seite 782-793

Sprache:

Englisch

Beteiligte Personen:

Dwivedi, Priyanka [VerfasserIn]
Singh, Pratibha [VerfasserIn]
Patel, Tejas K [VerfasserIn]
Bajpai, Vijeta [VerfasserIn]
Kabi, Ankita [VerfasserIn]
Singh, Yashpal [VerfasserIn]
Sharma, Santosh [VerfasserIn]
Kishore, Surekha [VerfasserIn]

Links:

Volltext

Themen:

98PI200987
Conservative treatment
Headache
Journal Article
Lidocaine
Meta-Analysis
Pain management
Post-dural puncture headache
Review
Sphenopalatine ganglion block

Anmerkungen:

Date Completed 07.11.2023

Date Revised 09.11.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.bjane.2023.06.002

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM359232515