The NLRP3 inflammasome in viral infection (Review)
The interplay between pathogen and host determines the immune response during viral infection. The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2023 |
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Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:28 |
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Enthalten in: |
Molecular medicine reports - 28(2023), 3 vom: 29. Sept. |
Sprache: |
Englisch |
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Beteiligte Personen: |
Zheng, Qiaoli [VerfasserIn] |
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Links: |
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Themen: |
Caspases |
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Anmerkungen: |
Date Completed 10.07.2023 Date Revised 10.08.2023 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.3892/mmr.2023.13047 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM359184340 |
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520 | |a The interplay between pathogen and host determines the immune response during viral infection. The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed | ||
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