The NLRP3 inflammasome in viral infection (Review)

The interplay between pathogen and host determines the immune response during viral infection. The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:28

Enthalten in:

Molecular medicine reports - 28(2023), 3 vom: 29. Sept.

Sprache:

Englisch

Beteiligte Personen:

Zheng, Qiaoli [VerfasserIn]
Hua, Chunting [VerfasserIn]
Liang, Qichang [VerfasserIn]
Cheng, Hao [VerfasserIn]

Links:

Volltext

Themen:

Caspases
EC 3.4.22.-
Inflammasome
Inflammasomes
Innate immune response
Interleukin-1beta
Journal Article
NLR Family, Pyrin Domain-Containing 3 Protein
NLRP3
Regulation
Review
Virus infection

Anmerkungen:

Date Completed 10.07.2023

Date Revised 10.08.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.3892/mmr.2023.13047

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM359184340