Programmed Cell Death in Asthma : Apoptosis, Autophagy, Pyroptosis, Ferroptosis, and Necroptosis

© 2023 Liu et al..

Bronchial asthma is a complex heterogeneous airway disease, which has emerged as a global health issue. A comprehensive understanding of the different molecular mechanisms of bronchial asthma may be an efficient means to improve its clinical efficacy in the future. Increasing research evidence indicates that some types of programmed cell death (PCD), including apoptosis, autophagy, pyroptosis, ferroptosis, and necroptosis, contributed to asthma pathogenesis, and may become new targets for future asthma treatment. This review briefly discusses the molecular mechanism and signaling pathway of these forms of PCD focuses on summarizing their roles in the pathogenesis and treatment strategies of asthma and offers some efficient means to improve clinical efficacy of therapeutics for asthma in the near future.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:16

Enthalten in:

Journal of inflammation research - 16(2023) vom: 10., Seite 2727-2754

Sprache:

Englisch

Beteiligte Personen:

Liu, Lu [VerfasserIn]
Zhou, Ling [VerfasserIn]
Wang, Ling-Ling [VerfasserIn]
Zheng, Peng-Dou [VerfasserIn]
Zhang, Feng-Qin [VerfasserIn]
Mao, Zhen-Yu [VerfasserIn]
Zhang, Huo-Jun [VerfasserIn]
Liu, Hui-Guo [VerfasserIn]

Links:

Volltext

Themen:

Asthma
Bronchial asthma
Journal Article
Programmed cell death
Review

Anmerkungen:

Date Revised 18.07.2023

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.2147/JIR.S417801

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM359167292