Qualitative and quantitative analysis of the chemical components in Yuquan capsules by using ultra-performance liquid chromatography-mass spectrometry
© 2023 Wiley-VCH GmbH..
The Yuquan capsules is a commonly used traditional Chinese Patent Medicine used for the treatment of diabetes mellitus. In this study, a high-throughput analytical method for identifying the chemical composition of Yuquan capsules was established for the first time by using ultra-performance liquid chromatography-quadrupole time of flight mass spectrometry. The data obtained were subjected to fragment analysis and this was combined with UNIFI processing of natural products. One-hundred sixteen compounds were characterized from Yuquan capsules. Twelve of the bioactive compounds were quantitatively analyzed by ultra-performance liquid chromatography-tandem triple quadrupole mass spectrometry. This study was undertaken to obtain a comprehensive chemical profile analysis as well as to evaluate the overall quality of Yuquan capsules. The results will provide a reference for the quality evaluation of different Yuquan preparations. In addition, the data will enable basic pharmacodynamic research into these extensively used capsules.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:46 |
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| Enthalten in: |
Journal of separation science - 46(2023), 16 vom: 01. Aug., Seite e2300148 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wu, Fangfang [VerfasserIn] |
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| Links: |
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| Themen: |
Capsules |
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| Anmerkungen: |
Date Completed 25.08.2023 Date Revised 25.08.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1002/jssc.202300148 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM359164188 |
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| 245 | 1 | 0 | |a Qualitative and quantitative analysis of the chemical components in Yuquan capsules by using ultra-performance liquid chromatography-mass spectrometry |
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| 500 | |a Date Revised 25.08.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 Wiley-VCH GmbH. | ||
| 520 | |a The Yuquan capsules is a commonly used traditional Chinese Patent Medicine used for the treatment of diabetes mellitus. In this study, a high-throughput analytical method for identifying the chemical composition of Yuquan capsules was established for the first time by using ultra-performance liquid chromatography-quadrupole time of flight mass spectrometry. The data obtained were subjected to fragment analysis and this was combined with UNIFI processing of natural products. One-hundred sixteen compounds were characterized from Yuquan capsules. Twelve of the bioactive compounds were quantitatively analyzed by ultra-performance liquid chromatography-tandem triple quadrupole mass spectrometry. This study was undertaken to obtain a comprehensive chemical profile analysis as well as to evaluate the overall quality of Yuquan capsules. The results will provide a reference for the quality evaluation of different Yuquan preparations. In addition, the data will enable basic pharmacodynamic research into these extensively used capsules | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Yuquan capsules | |
| 650 | 4 | |a qualitative analysis | |
| 650 | 4 | |a quality control | |
| 650 | 4 | |a quantitative analysis | |
| 650 | 4 | |a traditional Chinese medicine | |
| 650 | 7 | |a Drugs, Chinese Herbal |2 NLM | |
| 650 | 7 | |a Capsules |2 NLM | |
| 700 | 1 | |a Tan, Zhien |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Taiping |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Mengli |e verfasserin |4 aut | |
| 700 | 1 | |a He, Yanmei |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Shimin |e verfasserin |4 aut | |
| 700 | 1 | |a Yu, Pan |e verfasserin |4 aut | |
| 700 | 1 | |a Ou, Min |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Lingjie |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Xijun |e verfasserin |4 aut | |
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