Stem cell therapy for traumatic brachial plexus injury
© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature..
Stem cell therapy is rapidly evolving, with preclinical studies showing various stem cell types successfully promoting peripheral nerve regeneration. Despite the lack of clinical studies demonstrating efficacy and safety, the number of commercial entities marketing and promoting this treatment direct to patients is also increasing. We describe three adult traumatic brachial plexus injury (BPI) patients who had stem cell therapies prior to consultation in a multidisciplinary brachial plexus clinic. No functional improvement was noted at long-term follow-up despite claims reported by the commercial entities. Considerations and implications of stem cell application in BPI patients are reviewed.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:165 |
|---|---|
| Enthalten in: |
Acta neurochirurgica - 165(2023), 8 vom: 30. Aug., Seite 2011-2014 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Lee, Ellen Y [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Case Reports |
|---|
| Anmerkungen: |
Date Completed 09.08.2023 Date Revised 15.08.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s00701-023-05675-7 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM358910013 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM358910013 | ||
| 003 | DE-627 | ||
| 005 | 20231226075739.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00701-023-05675-7 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1196.xml |
| 035 | |a (DE-627)NLM358910013 | ||
| 035 | |a (NLM)37389748 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Lee, Ellen Y |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Stem cell therapy for traumatic brachial plexus injury |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 09.08.2023 | ||
| 500 | |a Date Revised 15.08.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature. | ||
| 520 | |a Stem cell therapy is rapidly evolving, with preclinical studies showing various stem cell types successfully promoting peripheral nerve regeneration. Despite the lack of clinical studies demonstrating efficacy and safety, the number of commercial entities marketing and promoting this treatment direct to patients is also increasing. We describe three adult traumatic brachial plexus injury (BPI) patients who had stem cell therapies prior to consultation in a multidisciplinary brachial plexus clinic. No functional improvement was noted at long-term follow-up despite claims reported by the commercial entities. Considerations and implications of stem cell application in BPI patients are reviewed | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Cell therapy | |
| 650 | 4 | |a Regenerative medicine | |
| 650 | 4 | |a Stem cells | |
| 650 | 4 | |a Traumatic brachial plexus injury | |
| 700 | 1 | |a Spinner, Robert J |e verfasserin |4 aut | |
| 700 | 1 | |a Mortazavi, Martin M |e verfasserin |4 aut | |
| 700 | 1 | |a Angius, Diana |e verfasserin |4 aut | |
| 700 | 1 | |a Adeeb, Nimer |e verfasserin |4 aut | |
| 700 | 1 | |a Bishop, Allen T |e verfasserin |4 aut | |
| 700 | 1 | |a Shin, Alexander Y |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Acta neurochirurgica |d 1950 |g 165(2023), 8 vom: 30. Aug., Seite 2011-2014 |w (DE-627)NLM00005609X |x 0942-0940 |7 nnns |
| 773 | 1 | 8 | |g volume:165 |g year:2023 |g number:8 |g day:30 |g month:08 |g pages:2011-2014 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00701-023-05675-7 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 165 |j 2023 |e 8 |b 30 |c 08 |h 2011-2014 | ||