Recent research on platelet-leukocyte aggregates and their role in the pathogenesis of Kawasaki disease
Activated platelets may interact with various types of leukocytes such as monocytes, neutrophils, dendritic cells, and lymphocytes, trigger intercellular signal transduction, and thus lead to thrombosis and synthesis of massive inflammatory mediators. Elevated levels of circulating platelet-leukocyte aggregates have been found in patients with thrombotic or inflammatory diseases. This article reviews the latest research on the formation, function, and detection methods of platelet-leukocyte aggregates and their role in the onset of Kawasaki disease, so as to provide new ideas for studying the pathogenesis of Kawasaki disease.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
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| Enthalten in: |
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 25(2023), 6 vom: 15. Juni, Seite 587-594 |
| Sprache: |
Chinesisch |
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| Weiterer Titel: |
血小板-白细胞聚集体及其在川崎病发病中的研究进展 |
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| Beteiligte Personen: |
Gao, Li-Chao [VerfasserIn] |
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| Links: |
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| Themen: |
Antiplatelet agent |
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| Anmerkungen: |
Date Completed 30.06.2023 Date Revised 07.07.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.7499/j.issn.1008-8830.2302066 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Activated platelets may interact with various types of leukocytes such as monocytes, neutrophils, dendritic cells, and lymphocytes, trigger intercellular signal transduction, and thus lead to thrombosis and synthesis of massive inflammatory mediators. Elevated levels of circulating platelet-leukocyte aggregates have been found in patients with thrombotic or inflammatory diseases. This article reviews the latest research on the formation, function, and detection methods of platelet-leukocyte aggregates and their role in the onset of Kawasaki disease, so as to provide new ideas for studying the pathogenesis of Kawasaki disease | ||
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