Hyperbaric oxygen therapy as an adjunctive treatment for COVID-19-associated mucormycosis : a report of two cases
OBJECTIVE.: We present the first two cases reported in Peru of the use of adjuvant hyperbaric oxygen therapy (HBOT) in patients with COVID-19-associated mucormycosis (CAM). The first case is a 41-year-old woman, with pain in the left side of the face and palatine region with purulent rhinorrhea for a month. Only an oroantral fistula was found during physical examination. The second case is a 35-year-old male, with decreased left visual acuity and palatal pain with a fistula, draining purulent secretion for four months. Both patients have history of diabetes, had moderate COVID-19 four months prior to admission, and received corticosteroid therapy for this diagnosis. Tomographic evaluation of both patients showed involvement of the maxillary sinus and surrounding bone tissue; both received diagnostic and therapeutic nasal endoscopy for debridement. Histological analysis showed that the samples were compatible with mucormycosis. The patients underwent debridement and were treated with amphotericin B deoxycholate; however, they presented torpid evolution. Then, HBOT was added and the patients showed an evident improvement after four weeks of treatment with subsequent controls without the presence of mucormycosis. We highlight the favorable evolution of these patients while receiving HBOT as treatment for a disease with high morbimortality, which emerged during the pandemic.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
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| Enthalten in: |
Revista peruana de medicina experimental y salud publica - 40(2023), 1 vom: 10. Jan., Seite 105-110 |
| Sprache: |
Spanisch |
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| Weiterer Titel: |
Oxigenoterapia hiperbárica como tratamiento complementario en mucormicosis asociada con la COVID-19: a propósito de dos casos |
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| Beteiligte Personen: |
Valencia-Caballero, Víctor [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 29.06.2023 Date Revised 29.06.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.17843/rpmesp.2023.401.11980 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM358785529 |
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| 520 | |a OBJECTIVE.: We present the first two cases reported in Peru of the use of adjuvant hyperbaric oxygen therapy (HBOT) in patients with COVID-19-associated mucormycosis (CAM). The first case is a 41-year-old woman, with pain in the left side of the face and palatine region with purulent rhinorrhea for a month. Only an oroantral fistula was found during physical examination. The second case is a 35-year-old male, with decreased left visual acuity and palatal pain with a fistula, draining purulent secretion for four months. Both patients have history of diabetes, had moderate COVID-19 four months prior to admission, and received corticosteroid therapy for this diagnosis. Tomographic evaluation of both patients showed involvement of the maxillary sinus and surrounding bone tissue; both received diagnostic and therapeutic nasal endoscopy for debridement. Histological analysis showed that the samples were compatible with mucormycosis. The patients underwent debridement and were treated with amphotericin B deoxycholate; however, they presented torpid evolution. Then, HBOT was added and the patients showed an evident improvement after four weeks of treatment with subsequent controls without the presence of mucormycosis. We highlight the favorable evolution of these patients while receiving HBOT as treatment for a disease with high morbimortality, which emerged during the pandemic | ||
| 650 | 4 | |a Case Reports | |
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| 700 | 1 | |a Huamán-Muñante, José |e verfasserin |4 aut | |
| 700 | 1 | |a Romaní-Montoro, Lourdes |e verfasserin |4 aut | |
| 700 | 1 | |a Vásquez-Zevallos, Norka |e verfasserin |4 aut | |
| 700 | 1 | |a Carozzi-Calvo, César |e verfasserin |4 aut | |
| 700 | 1 | |a Chian-García, Cesar |e verfasserin |4 aut | |
| 700 | 1 | |a Hernández-Chávez, Hugo |e verfasserin |4 aut | |
| 700 | 1 | |a Agustín-Paredes, Cristhian |e verfasserin |4 aut | |
| 700 | 1 | |a Rosa, Esteban Vergara-de la |e verfasserin |4 aut | |
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