Optical, structural and antibacterial properties of silver nanoparticles and DNA-templated silver nanoclusters

Silver nanoparticles (AgNPs) are increasingly considered for biomedical applications as drug-delivery carriers, imaging probes and antibacterial agents. Silver nanoclusters (AgNCs) represent another subclass of nanoscale silver. AgNCs are a promising tool for nanomedicine due to their small size, structural homogeneity, antibacterial activity and fluorescence, which arises from their molecule-like electron configurations. The template-assisted synthesis of AgNCs relies on organic molecules that act as polydentate ligands. In particular, single-stranded nucleic acids reproducibly scaffold AgNCs to provide fluorescent, biocompatible materials that are incorporable in other formulations. This mini review outlines the design and characterization of AgNPs and DNA-templated AgNCs, discusses factors that affect their physicochemical and biological properties, and highlights applications of these materials as antibacterial agents and biosensors.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

Nanomedicine (London, England) - 18(2023), 9 vom: 01. Apr., Seite 769-782

Sprache:

Englisch

Beteiligte Personen:

Danai, Leyla [VerfasserIn]
Rolband, Lewis A [VerfasserIn]
Perdomo, Valentina Abondano [VerfasserIn]
Skelly, Elizabeth [VerfasserIn]
Kim, Taejin [VerfasserIn]
Afonin, Kirill A [VerfasserIn]

Links:

Volltext

Themen:

3M4G523W1G
9007-49-2
Anti-Bacterial Agents
Antibacterial
Biosensors
DNA
Drug Carriers
Journal Article
Nanoscale silver
Nucleic Acids
Research Support, N.I.H., Extramural
Review
Silver
Silver nanoclusters
Silver nanoparticles

Anmerkungen:

Date Completed 30.06.2023

Date Revised 02.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.2217/nnm-2023-0082

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM358469902