Effects of dorsolateral prefrontal cortex stimulation on network topological attributes in young individuals with high-level perceived stress : A randomized controlled trial
Copyright © 2023 Elsevier B.V. All rights reserved..
Individuals with high-level perceived stress are at higher risk of developing a psychiatric disorder. While repetitive transcranial magnetic stimulation (rTMS) is effective for improving emotional symptoms, there is little evidence of its effect on perceived stress. This randomized sham-controlled trial investigated the effect of rTMS on ameliorating high-level stress and explored the associated changes in brain network activity. Fifty participants with high-level perceived stress were randomly assigned to either the active or sham rTMS group and received 12 active/sham rTMS sessions over four weeks (three per week). Perceived stress score (PSS), Chinese affective scale (CAS) normal and now statuses, and functional network topology were measured. Our results showed greater improvements in PSS and CAS_Normal scores, and reduced path length in the default mode network after active rTMS. Functional activations of the angular gyrus, posterior insula, and prefrontal cortex were also modulated in the active group. There were significant associations between posterior insula efficiency and PSS scores, and between angular efficiency and CAS_Now scores in the active group. These cumulative findings suggest rTMS as a promising intervention for recovery from high-level perceived stress.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:326 |
|---|---|
| Enthalten in: |
Psychiatry research - 326(2023) vom: 15. Aug., Seite 115297 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
He, Youze [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 02.08.2023 Date Revised 02.08.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.psychres.2023.115297 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM358225841 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM358225841 | ||
| 003 | DE-627 | ||
| 005 | 20231226074306.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.psychres.2023.115297 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1194.xml |
| 035 | |a (DE-627)NLM358225841 | ||
| 035 | |a (NLM)37320991 | ||
| 035 | |a (PII)S0165-1781(23)00247-0 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a He, Youze |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effects of dorsolateral prefrontal cortex stimulation on network topological attributes in young individuals with high-level perceived stress |b A randomized controlled trial |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 02.08.2023 | ||
| 500 | |a Date Revised 02.08.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier B.V. All rights reserved. | ||
| 520 | |a Individuals with high-level perceived stress are at higher risk of developing a psychiatric disorder. While repetitive transcranial magnetic stimulation (rTMS) is effective for improving emotional symptoms, there is little evidence of its effect on perceived stress. This randomized sham-controlled trial investigated the effect of rTMS on ameliorating high-level stress and explored the associated changes in brain network activity. Fifty participants with high-level perceived stress were randomly assigned to either the active or sham rTMS group and received 12 active/sham rTMS sessions over four weeks (three per week). Perceived stress score (PSS), Chinese affective scale (CAS) normal and now statuses, and functional network topology were measured. Our results showed greater improvements in PSS and CAS_Normal scores, and reduced path length in the default mode network after active rTMS. Functional activations of the angular gyrus, posterior insula, and prefrontal cortex were also modulated in the active group. There were significant associations between posterior insula efficiency and PSS scores, and between angular efficiency and CAS_Now scores in the active group. These cumulative findings suggest rTMS as a promising intervention for recovery from high-level perceived stress | ||
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Brain network | |
| 650 | 4 | |a Perceived stress | |
| 650 | 4 | |a Prefrontal cortex | |
| 650 | 4 | |a Repetitive transcranial magnetic stimulation | |
| 650 | 4 | |a Topological attributes | |
| 650 | 4 | |a Young adults | |
| 700 | 1 | |a Li, Zhaoying |e verfasserin |4 aut | |
| 700 | 1 | |a Cao, Lei |e verfasserin |4 aut | |
| 700 | 1 | |a Han, Mengyu |e verfasserin |4 aut | |
| 700 | 1 | |a Tu, Jingnan |e verfasserin |4 aut | |
| 700 | 1 | |a Deng, Haiying |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Zhenming |e verfasserin |4 aut | |
| 700 | 1 | |a Geng, Xiujuan |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Jingsong |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Psychiatry research |d 1982 |g 326(2023) vom: 15. Aug., Seite 115297 |w (DE-627)NLM000464988 |x 1872-7123 |7 nnns |
| 773 | 1 | 8 | |g volume:326 |g year:2023 |g day:15 |g month:08 |g pages:115297 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.psychres.2023.115297 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 326 |j 2023 |b 15 |c 08 |h 115297 | ||